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Circadian disruption induced by light-at-night accelerates aging and promotes tumorigenesis in young but not in old rats
TLDR
It is concluded that circadian disruption induced by light-at-night started at the age of 1 month accelerates aging and promotes tumorigenesis in rats, however failed affect survival when started atThe age of 14 months. Expand
Morphologic changes in the pineal gland of rats exposed to continuous darkness
TLDR
The activity of mammalian pineal can be altered by light conditions to which the animal is exposed and no significant differences in nuclear characteristics of intermediate type were found between rats kept in LD and those kept in DD. Expand
Antioxidant System and Energy Provision of the Rat Heart during Aging Depend on Illumination Regimen and Are Resistant to Exogenous Melatonin
TLDR
Activities of antioxidant enzymes, vitamin E level, lactate dehydrogenase isoenzyme spectrum, and effects of melatonin on these parameters were studied in the myocardium of rats exposed to different illumination regimens. Expand
The Mercury Content and Antioxidant System in Insectivorous Animals (Insectivora, Mammalia) and Rodents (Rodentia, Mammalia) of Various Ecogenesis Conditions
TLDR
The results indicate that mercury accumulation in the tissue depends on the age, tissue type, and diet of the species, and a correlation between mercury accumulation and catalase activity in the kidneys of the animals studied was found. Expand
Physiological and Biochemical Mechanisms of Lifespan Regulation in Rats Kept Under Various Light Conditions.
TLDR
Elevated activity of the antioxidant system extends the lifespan, while at the same time slowing down pubescence and altering the morpho-functional properties of leukocytes in blood, which depends on the level of melatonin produced by the pineal gland. Expand
Luzindole accelerates the aging of estrous function of female rats
TLDR
The dynamics of aging of the estrous function of female rats kept in the conditions of standard vivarium lighting that received luzindolee—a blocker of melatonin receptors was investigated, showing an increased duration of the ovulatory cycle and the early development of persistent estrus. Expand
Constant darkness conditions modulate the effects of melatonin and luzindole on the antioxidant enzyme activities and levels of retinol and α-tocopherol in rats
This study was conducted to evaluate the effects of both exogenous melatonin and melatonin receptor antagonist luzindole on the activities of antioxidant enzymes (AOE) (superoxide dismutase, SOD;Expand
Morphology and Composition of Peripheral Blood Cells during Hibernation in Bats (Chiroptera, Vespertilionidae) of Northwestern Russia
TLDR
Interspecific differences in the morphology of neutrophils, the total number, the absolute and relative content of certain types of leukocytes, and the size of the erythrocyte surface area have been established. Expand
Hematological Parameters in Hibernating Eptesicus nilssonii (Mammalia: Chiroptera) Collected in Northern European Russia
TLDR
Hibernating E. nilssonii were found to have a low total WBC count similar to other hibernators; no significant variation was noted during hibernation, and differential leukocyte count showed a significant reduction in total monocytes in winter. Expand
Light pollution, desynchronosis, and aging: State of the problem and solutions
TLDR
It was revealed that light pollution and disturbance of the photoperiod lead to desynchronosis and, as a result, to premature aging of the organism and age-associated diseases. Expand
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