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Extended-spectrum beta-lactamase-producing Enterobacteriaceae in Bulgarian hospitals.
The aim of the study was to describe the emergence, the spread, and the prevalence of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in Bulgaria. Over eight years (1996-2003),Expand
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Antibiotic policies in Central Eastern Europe.
To assess the antibiotic policies in Central Eastern European (CEE) countries, a questionnaire on the prevalence of resistance, antibiotic consumption data for ambulatory and hospital care andExpand
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Extended-spectrum beta-lactamase (ESBL) CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae in Sofia, Bulgaria.
During a survey of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae in Bulgaria in 2001-2002, three isolates from Sofia (two Escherichia coli, one Klebsiella pneumoniae) showedExpand
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Multicentre investigation of carbapenemase-producing Klebsiella pneumoniae and Escherichia coli in Bulgarian hospitals - Interregional spread of ST11 NDM-1-producing K. pneumoniae.
AIM The aim of this study was to investigate the mechanisms of beta-lactam-resistance and the clonal relatedness of carbapenem-nonsusceptible Klebsiella pneumoniae and Escherichia coli isolates,Expand
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SURGICAL PERSONNEL' ADHERENCE TO ANTIBIOTIC POLICIES
SUMMARY - Objectives. This work aimed at studying the adherence of personnel of the Surgery clinic of our institute to antibiotic policies in place. - Methods. Antimicrobial resistance surveillanceExpand
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Synthesis and preliminary antimicrobial evaluation of new 7-(N-pyrrolyl) derivatives of cephalosporins.
A series of seven new cephalosporins was prepared for preliminary microbiological evaluation by N-acylation of 7-aminocephalosporanic acid with substituted N-pyrrolylcarboxylic acids via mixedExpand
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Key issues in developing antibiotic policies: from an institutional level to Europe-wide. European Study Group on Antibiotic Policy (ESGAP), Subgroup III.
  • E. Keuleyan, M. Gould
  • Business, Medicine
  • Clinical microbiology and infection : the…
  • 1 December 2001
Establishment of a rational antibiotic policy (RAP) is a key issue for both better care of patients and combating antimicrobial resistance [1-5]. The problem of rational antibiotic use is complexExpand
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New Variant of CTX-M-Type Extended-Spectrum β-Lactamases, CTX-M-71, with a Gly238Cys Substitution in a Klebsiella pneumoniae Isolate from Bulgaria
ABSTRACT A single Klebsiella pneumoniae strain isolated in a Bulgarian hospital was found to produce CTX-M-71, a new CTX-M variant characterized by one amino acid substitution from glycine toExpand
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CTX-M-3 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and dissemination of the plasmidic blaCTX-M-3 in Bulgaria
A new group of extended-spectrum beta-lactamases (ESBLs) against which cefotaxime and ceftriaxone exhibit higher minimum inhibitory concentrations than ceftazidime was discovered at the beginning ofExpand
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