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The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension.
BACKGROUND Primary pulmonary hypertension is a progressive, fatal disease of unknown cause. Vasodilator drugs have been used as a treatment, but their efficacy is uncertain. METHODS We treated 64Expand
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Neurohormonal activation in patients with right ventricular failure from pulmonary hypertension: relation to hemodynamic variables and endothelin levels.
OBJECTIVES This study sought to determine whether neurohormonal activation occurs in isolated right heart failure. BACKGROUND Neurohormonal activation appears to parallel the severity of left heartExpand
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Autoantibodies against platelet glycoprotein Ib/IX: a frequent finding in autoimmune thrombocytopenic purpura
Summary Many autoantibodies involved in the pathogenesis of autoimmune thrombocytopenic purpura (AITP) are directed against epitopes on platelet glycoproteins (GP). These autoantibodies are aExpand
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Ant-gardens of tropical Asian rainforests
Ant-garden (AG) associations are systems of epiphytic plants and arboricolous (i.e., tree-living) ants, in which the ants build fragile carton nests containing organic material. They collect andExpand
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High dose titration of calcium channel blocking agents for primary pulmonary hypertension: guidelines for short-term drug testing.
Forty-seven patients with primary pulmonary hypertension were evaluated with a dose titration protocol utilizing nifedipine (20 mg orally) or diltiazem (60 mg orally) given every hour until maximalExpand
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Comparative acute effects of adenosine and prostacyclin in primary pulmonary hypertension.
Vasodilators have been a main focus of therapy for primary pulmonary hypertension. Adenosine and prostacyclin have been shown to reduce pulmonary vascular resistance acutely in these patients. InExpand
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Short-term effectiveness of nifedipine in secondary pulmonary hypertension.
Abstract Vasodilators have been used as an effective treatment in patients with pulmonary hypertension. In some patients with primary pulmonary hypertension, dramatic successes have occurredExpand
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Effects of adenosine in combination with calcium channel blockers in patients with primary pulmonary hypertension.
OBJECTIVES The purpose of this study was to evaluate the effects of vasodilator combination therapy in patients with primary pulmonary hypertension. BACKGROUND Calcium channel blockers andExpand
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Validity of applying adult TRISS analysis to injured children.
Injury severity measures are becoming increasingly important for quality assurance and injury research. TRISS analysis, which uses the Revised Trauma Score (RTS) and Injury Severity Score (ISS) toExpand
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Ant-Gardens on the giant bamboo Gigantochloa scortechinii (Poaceae) in West-Malaysia
Summary. We report the first experimental evidence of seed collecting behavior in an ant-garden-inhabiting ant species in the Palaeotropics.¶Vascular epiphytes growing on the giant bambooExpand
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