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Improvement of effect of water-in-oil microemulsion as an oral delivery system for fexofenadine: in vitro and in vivo studies
TLDR
Novel w/o microemulsion plays an important role in enhancing oral bioavailability of low permeability drugs, and is compared with Fexofen® syrup in in vitro and in vivo studies. Expand
Extended release lipophilic indomethacin microspheres: formulation factors and mathematical equations fitted drug release rates.
TLDR
The release of indomethacin was studied on the basis of USP criteria and the effects of drug-lipid ratio, the size of microspheres and carboxymethylcellulose sodium (CMC-Na) added as a hydrophilic polymer on the drug release were investigated. Expand
Permeation studies and histological examination of sheep nasal mucosa following administration of different nasal formulations with or without absorption enhancers.
This study was designed to investigate the possible histological effects of different intranasal (IN) formulations of indomethacin (IND) on nasal mucosa in sheep. For this purpose, oil-in-water (O/W)Expand
In vitro–in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate
TLDR
The results showed that FEX has a low permeability in the paracellular permeability as well a potential inhibition of secretion mediated by P-glycoprotein (Pgp), and its permeability increased with presence of SDS. Expand
Permeation Studies and Histological Examination of Sheep Nasal Mucosa Following Administration of Different Nasal Formulations with or without Absorption Enhancers
This study was designed to investigate the possible histological effects of different intranasal (IN) formulations of indomethacin (IND) on nasal mucosa in sheep. For this purpose, oil-in-water (O/W)Expand
Effect of grapefruit juice on bioavailability of montelukast
The aim of this study was to investigate possible interactions between grapefruit juice and montelukast for up to 4 hours.
Reabsorption of ascites and the factors that affect this process in cirrhosis.
TLDR
The size of lymphatic stomata in scanning electron microscopy depictions was increased, and lymphatic lacunae were dilated in immunohistochemical studies in the cirrhotic patients with ascites, but these findings were not uniform in every cirrhosis patient, suggesting the volume and viscosity of ascites seem to influence its reabsorption rate. Expand
Soybean Oil: Production Process, Benefits and Uses in Pharmaceutical Dosage Form
Vegetable oils are the most important source of fat in the human diet. Derived from an array of vegetable sources, oils are extracted and processed for a variety of food uses. In the demanding andExpand
Release Characteristics of Implantable Cylindrical Polyethylene Matrices
TLDR
The geometrical relationship between a hemisphere and a cylinder has been investigated for controlled‐release systems and found that the hemisphere dominates the cylinder in terms of volume and the cylinder dominates the volume of the hemisphere. Expand
Effects of pesticides used in agriculture on the development of precocious puberty
TLDR
The presence and levels of pesticides in serum and adipose tissues were not related to precocious puberty (PP), and the mechanisms that lead to PP may also result in obesity, and obesity may be the underlying cause for PP in this group. Expand
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