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Current methods for capsular typing of Streptococcus pneumoniae.
Streptococcus pneumoniae is a major respiratory tract pathogen causing pneumococcal disease mainly in children aged less than five years and in the elderly. Ninety-eight different capsular typesExpand
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Prevalence of Streptococcus pneumoniae serotypes causing invasive and non-invasive disease in South East Asia: a review.
BACKGROUND Streptococcus pneumoniae is a major cause of bacterial infections resulting in significant morbidity and mortality worldwide. Currently, up to 13 serotypes are included in pneumococcalExpand
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  • Open Access
Genetic diversity of Streptococcus pneumoniae causing meningitis and sepsis in Singapore during the first year of PCV7 implementation
Streptococcus pneumoniae is a major cause of sepsis, meningitis and respiratory disease worldwide. Pneumococcal conjugate vaccines (PCVs) have now been implemented in many countries worldwide,Expand
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Risk factor profiles and clinical outcomes for children and adults with pneumococcal infections in Singapore: A need to expand vaccination policy?
Invasive pneumococcal infection is a major cause of morbidity and mortality worldwide despite the availability of pneumococcal vaccines. The aim of this study was to re-evaluate the clinicalExpand
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COVID-19 epidemic severity is associated with timing of non-pharmaceutical interventions
Background: Unprecedented public health interventions including travel restrictions and national lockdowns have been implemented to stem the COVID-19 epidemic, but the effectiveness ofExpand
Population genomics of disease-causing Streptococcus pneumoniae in Singapore
The World Health Organization (WHO) reports that approximately 500,000 deaths in children aged 0-59 months occur due to pneumococcal infections and that, in the developing world, pneumococcalExpand