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Analysis of the motor effects of 13-norleucine motilin on the rabbit, guinea pig, rat, and human alimentary tract in vitro.
Motor effects of 13-norleucine motilin (13-Nle-M), a synthetic analog of motilin and biologically equivalent to the natural polypeptide, on the rabbit, guinea pig, rat, and human alimentary tractExpand
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The inhibition of human immunodeficiency virus proteases by 'interface peptides'.
The active human immunodeficiency virus type 1 (HIV-1) protease has a homodimeric structure, the subunits are connected by an 'interface' beta-sheet formed by the NH2- and COOH-terminal amino acidExpand
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Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A.
Crystal structure studies have shown that cleaved and intact serpins differ essentially in the topology of beta-sheet A. This is five-stranded in the intact molecules and six-stranded after cleavageExpand
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Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzyme.
GTP cyclohydrolase I catalyses the first and rate-limiting step of tetrahydrobiopterin biosynthesis. Its expression is regulated by interferon-gamma or kit ligand in a tissue-specific manner. ThreeExpand
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Thermodynamic partitioning model for hydrophobic binding of polypeptides by GroEL. I. GroEL recognizes the signal sequences of beta-lactamase precursor.
From equilibrium measurements with urea we found a three-state thermodynamic and kinetic folding behavior for the precursor and mature form of Escherichia coli beta-lactamase TEM2. The thermodynamicExpand
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Human anti-p68 autoantibodies recognize a common epitope of U1 RNA containing small nuclear ribonucleoprotein and influenza B virus
Autoantibodies from patients with systemic rheumatic diseases were used to map antigenic sites on the 68-kD autoantigen (p68) associated with (U1)RNA-containing small nuclear ribonucleoproteinExpand
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Intravenous 13-Nle-motilin increases the human lower esophageal sphincter pressure.
UNLABELLED To elucidate whether, in principle, motilin could serve a role in LESP regulation, the effects of 13-norleucine-motilin (13-nle-m)-synthetic analogue of motilin and biologically just asExpand
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Interaction of metal ions with gastrointestinal hormones
The biological action of the gastrin hormones is confined to the C-terminal tetrapeptide amide TrpMet-Asp-Phe-NH2 [2-51. The physiological role of the remaining peptide sequences is, however, stillExpand
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Purification of coniferyl alcohol dehydrogenase from Rhodococcus erythropolis
Publisher Summary The coniferyl alcohol dehydrogenase from Rhodococcus erythropolis catalyzes the pyridine nucleotide-dependent oxidation of coniferyl alcohol with the formation of NADH and theExpand
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Structural transition of α1‐antitrypsin by a peptide sequentially similar to β‐strand s4A
Crystal structure studies have shown that cleaved and intact serpins differ essentially in the topology of β-sheet A. This is five-stranded in the intact molecules and six-stranded after cleavage byExpand
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