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Analysis of the motor effects of 13-norleucine motilin on the rabbit, guinea pig, rat, and human alimentary tract in vitro.
Motor effects of 13-norleucine motilin (13-Nle-M), a synthetic analog of motilin and biologically equivalent to the natural polypeptide, on the rabbit, guinea pig, rat, and human alimentary tract… Expand
The inhibition of human immunodeficiency virus proteases by 'interface peptides'.
The active human immunodeficiency virus type 1 (HIV-1) protease has a homodimeric structure, the subunits are connected by an 'interface' beta-sheet formed by the NH2- and COOH-terminal amino acid… Expand
Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A.
- A. J. Schulze, U. Baumann, S. Knof, E. Jaeger, R. Huber, C. Laurell
- European journal of biochemistry
Crystal structure studies have shown that cleaved and intact serpins differ essentially in the topology of beta-sheet A. This is five-stranded in the intact molecules and six-stranded after cleavage… Expand
Human GTP cyclohydrolase I: only one out of three cDNA isoforms gives rise to the active enzyme.
GTP cyclohydrolase I catalyses the first and rate-limiting step of tetrahydrobiopterin biosynthesis. Its expression is regulated by interferon-gamma or kit ligand in a tissue-specific manner. Three… Expand
Thermodynamic partitioning model for hydrophobic binding of polypeptides by GroEL. I. GroEL recognizes the signal sequences of beta-lactamase precursor.
- R. Zahn, S. E. Axmann, K. P. Rücknagel, E. Jaeger, A. Laminet, A. Plückthun
- Chemistry, Medicine
- Journal of molecular biology
- 15 September 1994
From equilibrium measurements with urea we found a three-state thermodynamic and kinetic folding behavior for the precursor and mature form of Escherichia coli beta-lactamase TEM2. The thermodynamic… Expand
Human anti-p68 autoantibodies recognize a common epitope of U1 RNA containing small nuclear ribonucleoprotein and influenza B virus
- H. Guldner, H. Netter, C. Szostecki, E. Jaeger, H. Will
- Biology, Medicine
- The Journal of experimental medicine
- 1 March 1990
Autoantibodies from patients with systemic rheumatic diseases were used to map antigenic sites on the 68-kD autoantigen (p68) associated with (U1)RNA-containing small nuclear ribonucleoprotein… Expand
Intravenous 13-Nle-motilin increases the human lower esophageal sphincter pressure.
UNLABELLED To elucidate whether, in principle, motilin could serve a role in LESP regulation, the effects of 13-norleucine-motilin (13-nle-m)-synthetic analogue of motilin and biologically just as… Expand
Interaction of metal ions with gastrointestinal hormones
- M. Palumbo, E. Jaeger, S. Knof, E. Peggion, E. Wünsch
- Chemistry, Medicine
- FEBS letters
- 22 September 1980
The biological action of the gastrin hormones is confined to the C-terminal tetrapeptide amide TrpMet-Asp-Phe-NH2 [2-51. The physiological role of the remaining peptide sequences is, however, still… Expand
Purification of coniferyl alcohol dehydrogenase from Rhodococcus erythropolis
- E. Jaeger
Publisher Summary The coniferyl alcohol dehydrogenase from Rhodococcus erythropolis catalyzes the pyridine nucleotide-dependent oxidation of coniferyl alcohol with the formation of NADH and the… Expand
Structural transition of α1‐antitrypsin by a peptide sequentially similar to β‐strand s4A
- A. J. Schulze, U. Baumann, S. Knof, E. Jaeger, R. Huber, Carl-Bertil Laurell
- 1 November 1990
Crystal structure studies have shown that cleaved and intact serpins differ essentially in the topology of β-sheet A. This is five-stranded in the intact molecules and six-stranded after cleavage by… Expand