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Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3).
The cloned organic anion transporters from rat, mouse, and winter flounder (rOAT1, mOAT1, fROAT) mediate the coupled exchange of alpha-ketoglutarate with multiple organic anions, includingExpand
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Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter.
We isolated and characterized a novel K-Cl cotransporter, KCC3, from human placenta. The deduced protein contains 1,150 amino acids. KCC3 shares 75-76% identity at the amino acid level with human,Expand
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Cloning, characterization, and gene organization of K-Cl cotransporter from pig and human kidney and C. elegans.
We isolated and characterized the cDNAs for the human, pig, and Caenorhabditis elegansK-Cl cotransporters. The pig and human homologs are 94% identical and contain 1,085 and 1,086 amino acids,Expand
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Molecular characterization of two novel transporters from human and mouse kidney and from LLC-PK1 cells reveals a novel conserved family that is homologous to bacterial and Aspergillus nucleobase
Nucleobase transport is important for the metabolism of nucleic acids and antiviral and antineoplastic drugs. This transport has been functionally described in several mammalian cells but has notExpand
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Molecular cloning and functional characterization of KCC 3 , a new KCl cotransporter
JOANNE E. RACE,1 FADI N. MAKHLOUF,1,2 PAUL J. LOGUE,2 FREDERICK H. WILSON,3 PHILIP B. DUNHAM,2 AND ELI J. HOLTZMAN1,4 1Renal Division, Department of Medicine, and 4Department of Biochemistry andExpand
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Cloning, characterization, and gene organization of K-Cl cotransporter from pig and human kidney and C. elegans.
We isolated and characterized the cDNAs for the human, pig, and Caenorhabditis elegans K-Cl cotransporters. The pig and human homologs are 94% identical and contain 1,085 and 1,086 amino acids,Expand
Molecular cloning and functional characterization of KCC3, a new K-Cl cotransporter.
We isolated and characterized a novel K-Cl cotransporter, KCC3, from human placenta. The deduced protein contains 1,150 amino acids. KCC3 shares 75-76% identity at the amino acid level with human,Expand