Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes
- E. Jäger, Yao-Tseng Chen, +9 authors A. Knuth
- Biology, Medicine
- The Journal of experimental medicine
- 19 January 1998
A growing number of human tumor antigens have been described that can be recognized by cytotoxic T lymphocytes (CTLs) in a major histocompatibility complex (MHC) class I–restricted fashion.… Expand
Chemotherapy for advanced gastric cancer.
- S. Al-Batran, E. Jäger, M. Scholz
- Medicine
- Journal of clinical oncology : official journal…
- 9 February 2007
Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie.
- S. Al-Batran, J. Hartmann, +17 authors E. Jäger
- Medicine
- Journal of clinical oncology : official journal…
- 20 March 2008
PURPOSE
This study was designed to compare fluorouracil, leucovorin, and oxaliplatin with fluorouracil, leucovorin, and cisplatin in patients with advanced gastric cancer.
PATIENTS AND METHODS… Expand
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans
- D. Sugiyama, H. Nishikawa, +10 authors S. Sakaguchi
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 14 October 2013
Significance Regulatory T (Treg) cells expressing the transcription factor FOXP3 play a critical role in suppressing antitumor immune responses. Here we found that, compared with peripheral blood T… Expand
A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens
- E. Stockert, E. Jäger, +6 authors L. Old
- Biology, Medicine
- The Journal of experimental medicine
- 20 April 1998
Evidence is growing for both humoral and cellular immune recognition of human tumor antigens. Antibodies with specificity for antigens initially recognized by cytotoxic T lymphocytes (CTLs), e.g.,… Expand
Identification of multiple cancer/testis antigens by allogeneic antibody screening of a melanoma cell line library.
- Y. Chen, A. O. Güre, +4 authors L. Old
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 9 June 1998
Cancer/testis (CT) antigens-immunogenic protein antigens that are expressed in testis and a proportion of diverse human cancer types-are promising targets for cancer vaccines. To identify new CT… Expand
Histopathological regression after neoadjuvant docetaxel, oxaliplatin, fluorouracil, and leucovorin versus epirubicin, cisplatin, and fluorouracil or capecitabine in patients with resectable gastric…
- S. Al-Batran, R. Hofheinz, +37 authors A. Tannapfel
- Medicine
- The Lancet. Oncology
- 1 December 2016
BACKGROUND
Docetaxel-based chemotherapy is effective in metastatic gastric and gastro-oesophageal junction adenocarcinoma, but has not yet been evaluated in the context of resectable patients. Here… Expand
SSX: A multigene family with several members transcribed in normal testis and human cancer
- Ali O. Gure, Ö. Türeci, +7 authors Y. Chen
- Biology, Medicine
- International journal of cancer
- 17 September 1997
Analysis of t(X;18) translocation in synovial sarcoma had previously led to the definition of the SSX2 gene, the fusion partner on chromosome X. Subsequent screening of testicular cDNA libraries… Expand
Acetylation of Stat1 modulates NF-kappaB activity.
- O. Krämer, D. Baus, +6 authors T. Heinzel
- Medicine
- Genes & development
- 2006
Acetylation of signaling molecules can lead to apoptosis or differentiation of carcinoma cells. The molecular mechanisms underlying these processes and the biological role of enzymes mediating the… Expand
Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE‐3 and presented by HLA‐A1
- M. Marchand, N. van Baren, +22 authors T. Boon
- Medicine
- International journal of cancer
- 18 January 1999
Thirty‐nine tumor‐bearing patients with metastatic melanoma were treated with 3 subcutaneous injections of the MAGE‐3.A1 peptide at monthly intervals. No significant toxicity was observed. Of the 25… Expand