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Detection of Four Plasmodium Species by Genus- and Species-Specific Loop-Mediated Isothermal Amplification for Clinical Diagnosis
Loop-mediated isothermal amplification, a novel nucleic acid amplification method, was developed for the clinical detection of four species of human malaria parasites and may provide a simple and reliable test for routine screening for malaria parasites in both clinical laboratories and malaria clinics in areas where malaria is endemic. Expand
Mixed infections with Opisthorchis viverrini and intestinal flukes in residents of Vientiane Municipality and Saravane Province in Laos
The results indicate that O. viverrini and several species of heterophyid and lecithodendriid flukes are endemic in these two riverside localities, and suggest that the intensity of infection and the relative proportion of fluke species vary by locality along the Mekong River basin. Expand
A survey of Enterobius vermicularis infection among children on western and southern coastal islands of the Republic of Korea.
E. vermicularis infection is highly prevalent among pre-school and primary school children living on the western and southern coastal islands of the Republic of Korea, and the need for efforts to control this infection is indicated. Expand
Genotype analysis of Cryptosporidium spp. prevalent in a rural village in Hwasun-gun, Republic of Korea.
It is suggested that human cryptosporidiosis in the studied area is caused by mixtures of C. hominis and C. parvum oocysts originating from both inhabitants and domestic animals. Expand
Genetic polymorphism in pvmdr1 and pvcrt-o genes in relation to in vitro drug susceptibility of Plasmodium vivax isolates from malaria-endemic countries.
In Korean isolates polymorphism as limited to the F1076L variant, and no isolates with high level of resistance were found by in vitro susceptibility determinations, which provide a baseline for future prospective drug studies in malaria-endemic areas. Expand
High prevalence of liver and intestinal fluke infections among residents of Savannakhet Province in Laos.
The results indicate that foodborne liver and intestinal fluke infections are prevalent among residents of Savannakhet Province, Laos. Expand
Mutations in the antifolate-resistance-associated genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium vivax isolates from malaria-endemic countries.
  • Feng Lu, C. Lim, +8 authors E. Han
  • Biology, Medicine
  • The American journal of tropical medicine and…
  • 1 September 2010
Findings suggests that the prevalence of mutations in pVDhfr and pvdhps in P. vivax isolates from different malaria-endemic countries is associated with selection pressure imposed by sulfadoxine-pyrimethamine. Expand
Molecular assessment of artemisinin resistance markers, polymorphisms in the k13 propeller, and a multidrug-resistance gene in the eastern and western border areas of Myanmar.
The low prevalence of K13 mutations and the absence of day 3 parasitaemic cases indicate that artemisinin resistance may not have spread to the western Myanmar border region. Expand
pLDH level of clinically isolated Plasmodium vivax and detection limit of pLDH based malaria rapid diagnostic test
The pLDH levels of P. vivax are the main explanation for the variations in the performance of p LDH-based RDTs, and comparing sensitivities of RDT may need to include targeted biomarker value of patients. Expand
Prevalence of Drug Resistance-Associated Gene Mutations in Plasmodium vivax in Central China
  • Feng Lu, B. Wang, +6 authors E. Han
  • Biology, Medicine
  • The Korean journal of parasitology
  • 26 November 2012
The study suggests that P. vivax populations in central China may still be relatively susceptible to chloroquine and sulfadoxine-pyrimethamine, and warranted further studies in relation to the parasite resistance to antifolate drugs. Expand