• Publications
  • Influence
Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on
Evolving definitions of frailty, and improved understanding of molecular and physiological declines in multiple systems that may increase vulnerability in frail, older adults has encouragedExpand
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Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study.
BACKGROUND The Short Physical Performance Battery (SPPB), which includes walking, balance, and chair stands tests, independently predicts mobility disability and activities of daily livingExpand
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The effects of exercise on falls in elderly patients. A preplanned meta-analysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques.
Objective. —To determine if short-term exercise reduces falls and fall-related injuries in the elderly. Design. —A preplanned meta-analysis of the seven Frailty and Injuries: Cooperative Studies ofExpand
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The effects of exercise on falls in elderly patients. A preplanned meta-analysis of the FICSIT Trials. Frailty and Injuries: Cooperative Studies of Intervention Techniques.
OBJECTIVE To determine if short-term exercise reduces falls and fall-related injuries in the elderly. DESIGN A preplanned meta-analysis of the seven Frailty and Injuries: Cooperative Studies ofExpand
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Efficacy of bladder training in older women with urinary incontinence.
The efficacy of bladder training was evaluated in a randomized clinical trial involving 123 noninstitutionalized women 55 years and older with urinary incontinence. Subjects were urodynamicallyExpand
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A comparison of effectiveness of biofeedback and pelvic muscle exercise treatment of stress incontinence in older community-dwelling women.
BACKGROUND Research using biofeedback as a treatment for sphincteric incontinence began with Kegel's early studies using a perineometer and pelvic muscle exercises demonstrating a 90% improvement inExpand
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Design and conduct of the CALERIE study: comprehensive assessment of the long-term effects of reducing intake of energy.
BACKGROUND In a robust and consistent manner, sustained caloric restriction (CR) has been shown to retard the aging process in a variety of animal species. Nonhuman primate studies suggest that CRExpand
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Health and function of participants in the Long Life Family Study: A comparison with other cohorts
Individuals from families recruited for the Long Life Family Study (LLFS) (n= 4559) were examined and compared to individuals from other cohorts to determine whether the recruitment targetingExpand
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The significance of sarcopenia in old age.
  • C. Dutta, E. Hadley
  • Medicine
  • The journals of gerontology. Series A, Biological…
  • 1 November 1995
Our knowledge of the significance of sarcopenia in old age is limited by a lack of epidemiologic data, an incomplete assessment of the pathophysiologic consequences of age-related decrements inExpand
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A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity.
BACKGROUND Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake, increases life span in many species. The implications for humans can be clarified by randomized controlledExpand
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