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Assessment of Oxidative Damage Induced by Acute Doses of Morphine Sulfate in Postnatal and Adult Rat Brain
The results indicate age-induced changes in cellular regulation and biochemical responses to oxidative stress induced by morphine show signs of decline in brain levels and Na+, K+-ATPase and total ATPase activity. Expand
Effect of testosterone and steroids homologues on indolamines and lipid peroxidation in rat brain
Results suggest that A steroid reduces TBARS in rat brain, perhaps as a result of the interaction between the testosterone unsaturated carbons and OH(-) groups with free radicals. Expand
The Role of Dopamine and Its Dysfunction as a Consequence of Oxidative Stress
The present review focuses on the therapeutic potential of antioxidant compounds as a coadjuvant treatment to conventional neurological disorders and introduces new potential targets for the development of therapeutic interventions based on antioxidant compounds. Expand
Mechanisms involved in the development of diabetic retinopathy induced by oxidative stress
The poor control of glucemy in pacients with DB has been shown contribute to the development of complications in eyes as DR, which is a significant complication in people with diabetes. Expand
Cerebrolysin and morphine decrease glutathione and 5-hydroxyindole acetic acid levels in fasted rat brain.
Results suggest that cerebrolysin as well as morphine induced changes in cellular regulation and biochemical responses to oxidative stress induced by moderate hypoglycaemia in brain. Expand
Oleic Acid Protects Against Oxidative Stress Exacerbated by Cytarabine and Doxorubicin in Rat Brain.
The results suggest that the reduction of dopamine and oxidant effect during cytarabine treatment could result in brain injury but could be prevented by oleic acid supplementation. Expand
Effects of marijuana and diazepam on lipid peroxidation, Na+ , K+ ATPase, and levels of glutathione and 5-HTP in rat brain.
Mar and Dz induced biochemical effects on the serotonergic metabolism, which can alter the development and function in rat brain, because it has also been involved in scavenging free radicals present there. Expand
Assessment of Antioxidant Effect of 2,5-Dihydroxybenzoic Acid and Vitamin A in Brains of Rats with Induced Hyperoxia
The aim of this study was to evaluate the effect of 2,5-dihydroxybenzoic acid, a salicylate derived from Acetyl salicylic acid (ASA) and vitamin A (vit A) on Na+, K+ ATPase enzyme and GSH levels inExpand
Effect of pentylenetetrazole and carbodiimide on oxidation stress markers in rat brain.
The aim of the present study is to evaluate the effect of pentylenetetrazole and carbodiimide on some biochemical markers of oxidative stress as nitric oxide metabolites, 5HT, Naπ Kπ ATPase and thiobarbituric acid in rat brain. Expand
Biochemical and histological changes produced by sweeteners and cytarabine in the brain of young rats
The results show that sweeteners as stevia or splenda may lead to the onset of unfavorable changes in dopamine and 5-HIAA, and Antioxidant effects may be involved. Expand