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New insights in the molecular biology and physiology of Streptococcus thermophilus revealed by comparative genomics.
Streptococcus thermophilus is a major dairy starter used for the manufacture of yoghurt and cheese. The access to three genome sequences, comparative genomics and multilocus sequencing analysesExpand
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Overall control of nitrogen metabolism in Lactococcus lactis by CodY, and possible models for CodY regulation in Firmicutes.
CodY, a pleiotropic transcriptional regulator conserved in low G+C species of Gram-positive bacteria, was previously described to be the central regulator of proteolysis in Lactococcus lactis. InExpand
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Pleiotropic transcriptional repressor CodY senses the intracellular pool of branched‐chain amino acids in Lactococcus lactis
Proteolysis is essential for supplying Lactococcus lactis with amino acids during growth in milk. Expression of the major components of the L. lactis proteolytic system, including the cell wallExpand
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Sulfur amino acid metabolism and its control in Lactococcus lactis IL1403.
Cysteine and methionine availability influences many processes in the cell. In bacteria, transcription of the specific genes involved in the synthesis of these two amino acids is usually regulated byExpand
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Transcriptional pattern of genes coding for the proteolytic system of Lactococcus lactis and evidence for coordinated regulation of key enzymes by peptide supply.
The transcription of 16 genes encoding 12 peptidases (pepC, pepN, pepX, pepP, pepA, pepF2, pepDA1, pepDA2, pepQ, pepT, pepM, and pepO1), P(I) and P(III) proteinases (prtP1 and prtP3), and threeExpand
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Intracellular effectors regulating the activity of the Lactococcus lactis CodY pleiotropic transcription regulator
CodY is a pleiotropic transcriptional regulator conserved in low‐G+C Gram‐positive bacteria. Two distinct signals have been shown independently to influence the activity of this regulator: the levelExpand
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Quorum-sensing regulation of the production of Blp bacteriocins in Streptococcus thermophilus.
The blp gene cluster identified in the genome sequences of Streptococcus thermophilus (blp(St)) LMG18311, CNRZ1066, and LMD-9 displays all the characteristics of a class II bacteriocin locus. In theExpand
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Fructose utilization in Lactococcus lactis as a model for low-GC gram-positive bacteria: its regulator, signal, and DNA-binding site.
In addition to its role as carbon and energy source, fructose metabolism was reported to affect other cellular processes, such as biofilm formation by streptococci and bacterial pathogenicity inExpand
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The dynamic protein partnership of RNA polymerase inBacillus subtilis
In prokaryotes, transcription results from the activity of a 400 kDa RNA polymerase (RNAP) protein complex composed of at least five subunits (2α, β, β′, ω). To ensure adequate responses to changingExpand
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Control of methionine synthesis and uptake by MetR and homocysteine in Streptococcus mutans.
MetR (formerly Smu.1225), a regulator of the LysR family, controls key genes for methionine supply in Streptococcus mutans. An S. mutans metR mutant is unable to transport l-methionine and to grow inExpand
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