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Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy
Tick-borne virus diseases of human interest in Europe.
- R. Charrel, H. Attoui, X. de Lamballerie
- MedicineClinical microbiology and infection : the…
- 1 December 2004
The epidemiology, clinical picture and methods for diagnosis are detailed in this review, and some of these viral pathogens have been classified in Categories A-C of potential bioterrorism agents by the Centers for Disease Control and Prevention.
Phylogenetic relationships and differential selection pressures among genotypes of dengue-2 virus.
It is determined that genotypes have experienced different selection pressures, with some evidence of positive selection in the Cosmopolitan genotype and one of the two Asian genotypes, but that the transition from sylvatic to human transmission was not accompanied by adaptive evolution of the E gene.
ICTV Virus Taxonomy Profile: Flaviviridae
The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases that infect mammals and birds and many are important human and veterinary pathogens.
The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket
The crystal structure of the Chikungunya virus macro domain with an RNA trimer shows a binding mode utilizing the same adenine-binding pocket as ADP-ribose, but avoiding the AMP binding site, which is the sole common feature in all macro domains.
Isolation of a novel species of flavivirus and a new strain of Culex flavivirus (Flaviviridae) from a natural mosquito population in Uganda
The discovery, isolation and characterization of two novel ‘insect-only’ flaviviruses from Entebbe, Uganda: a novel lineage tentatively designated Nakiwogo virus (NAKV) and a new strain of CxFV.
Molecular epidemiology of Rabbit haemorrhagic disease virus.
RHDV circulated as an apparently avirulent virus throughout Britain more than 50 years ago and more than 30 years before the disease itself was identified, based on molecular phylogenetic analysis of British and European RHDV sequences.
Origins, evolution, and vector/host coadaptations within the genus Flavivirus.
Phylogenetic relationships of flaviviruses correlate with their epidemiology, disease association and biogeography.
- M. Gaunt, A. Sall, X. de Lamballerie, A. K. Falconar, T. I. Dzhivanian, E. Gould
- BiologyThe Journal of general virology
- 1 August 2001
Phylogenetic analysis of the Flavivirus genus revealed an extensive series of clades defined by their epidemiology and disease associations, which revealed distinct geographical clusters in either the Old World or the New World, which for mosquito-borne viruses may reflect an Old World origin.