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Sideritis spp.: uses, chemical composition and pharmacological activities--a review.
TLDR
The aim of this review is to provide a comprehensive overview on the botanical, phytochemical and pharmacological aspects from the genus Sideritis, with the objective of establishing scientific basis that explains its ethnopharmacological use. Expand
Terpene compounds in nature: a review of their potential antioxidant activity.
TLDR
This review provides a complete overview of the natural terpenes with potential antioxidant properties, focusing on their source, structures, antioxidant mechanisms through which they exert their pharmacological and possible therapeutic activities. Expand
Mitochondria-Targeted Protective Compounds in Parkinson's and Alzheimer's Diseases
TLDR
An overview of the involvement of mitochondrial dysfunction in Parkinson's and Alzheimer's diseases is provided, with particular attention to in vitro and in vivo studies on promising endogenous and exogenous mitochondria-targeted protective compounds. Expand
Phytochemical composition, antioxidant and cytoprotective activities of essential oil of Salvia lavandulifolia Vahl
Abstract The use of aromatic plants for food flavoring and medicinal purposes began a long time ago. The chemical composition of two essential oils from Salvia lavandulifolia from Spain differing inExpand
Evaluation of the adaptogenic potential exerted by ginsenosides Rb1 and Rg1 against oxidative stress-mediated neurotoxicity in an in vitro neuronal model
TLDR
Ginsenosides Rb1 and Rg1 exhibit neuroprotective potential which is achieved, at least in part, via mitochondrial protection and the plausible involvement of Nrf2 pathway activation. Expand
Major selected monoterpenes α-pinene and 1,8-cineole found in Salvia lavandulifolia (Spanish sage) essential oil as regulators of cellular redox balance
TLDR
These findings demonstrate for the first time the effects of the monoterpenes 1,8-cineole and α-pinene identified in S. lavandulifolia essential oil as regulators of cellular redox balance in astrocytes. Expand
HPLC isolation of antioxidant constituents from Xanthoparmelia spp.
TLDR
Both lichens extracts and all isolated compounds protected U373 MG cells from hydrogen peroxide-induced damage, suggesting that they could act as antioxidant agents in those neurodegenerative disorders associated with oxidative damage, such as Alzheimer's disease and Parkinson's disease. Expand
Regulation of redox status in neuronal SH-SY5Y cells by blueberry (Vaccinium myrtillus L.) juice, cranberry (Vaccinium macrocarpon A.) juice and cyanidin.
TLDR
Blueberry and cranberry juices as well as cyanidin increased mitochondrial activity and reduced intracellular ROS production and lipid peroxidation induced by hydrogen peroxide, and in vitro antioxidant capacities were confirmed by ORAC and FRAP assays demonstrating the potential of cyanid in and cyanidIn-containing products for pharmaceutical or nutritional applications to prevent oxidative stress in neuronal cells. Expand
Polyphenol-associated oxidative stress and inflammation in a model of LPS-induced inflammation in glial cells: do we know enough for responsible compounding?
TLDR
Current data highlight the potential risk for antioxidant toxicity that is linked to high dose supplementation with single compound antioxidants, and research focused at elucidating synergistic effects between different antioxidants is required to minimise risk of adverse effects. Expand
Potential Neuroprotective Activity of Ginseng in Parkinson’s Disease: A Review
TLDR
All research works published in MEDLINE/PubMed within the last decade by utilizing the following combination of the keywords: “Ginseng, ginsenosides, neuroprotection and Parkinson’s disease” are included. Expand
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