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Box-Behnken design: an alternative for the optimization of analytical methods.
The present paper describes fundamentals, advantages and limitations of the Box-Behnken design (BBD) for the optimization of analytical methods. It establishes also a comparison between this designExpand
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Statistical designs and response surface techniques for the optimization of chromatographic systems.
This paper describes fundamentals and applications of multivariate statistical techniques for the optimization of chromatographic systems. The surface response methodologies: central compositeExpand
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Use of slurry sampling for the direct determination of zinc in yogurt by high resolution-continuum source flame atomic absorption spectrometry.
This paper presents an analytical procedure for the direct determination of zinc in yogurt employing sampling slurry and high resolution-continuum source flame atomic absorption spectrometry (HR-CSExpand
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Determination of copper in powdered chocolate samples by slurry-sampling flame atomic-absorption spectrometry
Chocolate is a complex sample with a high content of organic compounds and its analysis generally involves digestion procedures that might include the risk of losses and/or contamination. TheExpand
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Thermoresistant xylanases from Trichoderma stromaticum: Application in bread making and manufacturing xylo-oligosaccharides.
The enzymes Xyl1 and Xyl2 from T. stromaticum were purified and identified by mass spectrometry (MALDI-TOF/MS). Xyl1 contained three proteins with similarity to xylanase family 10, 62 andExpand
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Determination and Evaluation of Metallothionein and Metals in Mugil cephalus (Mullet) from Pontal Bay, Brazil
To assess environmental contamination, studies have been increasingly carried out using biomarkers to diagnose the effects of toxic metal exposure, such as metallothionein (MT). In this context, theExpand
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Evaluation and Application of the Internal Standard Technique for the Direct Determination of Copper in Fruit Juices Employing Fast Sequential Flame Atomic Absorption Spectrometry
Abstract The present paper describes the evaluation and application of internal standard for the determination of copper in fruit juices, employing Fast Sequential Flame Atomic AbsorptionExpand
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Evaluation of macro and micronutrient elements content from soft drinks using principal component analysis and Kohonen self-organizing maps.
This study approaches the determination of nine elements from Brazilian carbonated soft drinks of several flavors and manufactures using inductively coupled plasma optical emission spectrometry (ICPExpand
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Slurry Sampling—An Analytical Strategy for the Determination of Metals and Metalloids by Spectroanalytical Techniques
Abstract This article critically overviews the state-of-the-art of slurry sampling as an approach for the minimization of sample preparation prior to the determination of metals and metalloids inExpand
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Application of Multivariate Techniques in Optimization of Spectroanalytical Methods
Abstract The present article describes fundamentals and applications of multivariate techniques used for the optimization of analytical procedures and systems involving spectroanalytical methods suchExpand
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