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Pharmacokinetics of N3-Benzylthymidine Possessing Hypnotic Activity in Mice
E. Furuta
,
Toshiyuki Kimura
,
M. Koshigami
,
J. Kuze
,
Kazuhito Watanabe
,
I. Yamamoto
Biology, Chemistry
15 October 1992
TLDR
N3-ByTd itself is a real hypnotic substance in mice, since these metabolites did not have any hypnotic activity, and the possible metabolic pathway is suggested to be N3-debenzylation and N 3-deribosylation.
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Hypnotic and sedative activities of N3-substituted uridine, thymidine and azauridine, and their action mechanism
I. Yamamoto
,
Kazuhito Watanabe
,
+4 authors
I. Ho
Chemistry
1 July 1990
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