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- Publications
- Influence
Mechanisms of Chronic State of Inflammation as Mediators That Link Obese Adipose Tissue and Metabolic Syndrome
- E. Fuentes, F. Fuentes, G. Vilahur, L. Badimón, I. Palomo
- Biology, Medicine
- Mediators of inflammation
- 13 June 2013
The metabolic syndrome is a cluster of cardiometabolic alterations that include the presence of arterial hypertension, insulin resistance, dyslipidemia, and abdominal obesity. Obesity is associated… Expand
Antioxidant and Antiplatelet Activities in Extracts from Green and Fully Ripe Tomato Fruits (Solanum lycopersicum) and Pomace from Industrial Tomato Processing
- E. Fuentes, R. Carle, +4 authors I. Palomo
- Biology, Medicine
- Evidence-based complementary and alternative…
- 17 February 2013
The consumption of fruits and vegetables is accepted to be one of the strategies to reduce risk factors for these diseases. The aim of this study was to examine potential relationships between the… Expand
Chlorogenic Acid Inhibits Human Platelet Activation and Thrombus Formation
- E. Fuentes, J. Caballero, M. Alarcón, A. Rojas, I. Palomo
- Chemistry, Medicine
- PloS one
- 5 March 2014
Background Chlorogenic acid is a potent phenolic antioxidant. However, its effect on platelet aggregation, a critical factor in arterial thrombosis, remains unclear. Consequently, chlorogenic… Expand
Primary and secondary haemostasis changes related to aging
- C. Sepúlveda, I. Palomo, E. Fuentes
- Medicine
- Mechanisms of Ageing and Development
- 1 September 2015
Life expectancy has increased in many countries as a result the world's population is aging. The projections indicate that the proportion of the elderly in a few decades will increase significantly.… Expand
Mauritia flexuosa Presents In Vitro and In Vivo Antiplatelet and Antithrombotic Activities
- E. Fuentes, Wilson Rodríguez-Pérez, +4 authors I. Palomo
- Medicine
- Evidence-based complementary and alternative…
- 18 December 2013
Fruit from the palm Mauritia flexuosa is one of the most important species in Peru, Venezuela, Brazil, Colombia, Bolivia, and Guyana. The present study aimed to investigate the antiplatelet and… Expand
Role of Platelet-Derived Microvesicles As Crosstalk Mediators in Atherothrombosis and Future Pharmacology Targets: A Link between Inflammation, Atherosclerosis, and Thrombosis
- L. Badimón, R. Suades, E. Fuentes, I. Palomo, T. Padró
- Medicine
- Front. Pharmacol.
- 31 August 2016
Reports in the last decade have suggested that the role of platelets in atherosclerosis and its thrombotic complications may be mediated, in part, by local secretion of platelet-derived microvesicles… Expand
Immune System Dysfunction in the Elderly.
- E. Fuentes, Manuel Fuentes, M. Alarcón, I. Palomo
- Biology, Medicine
- Anais da Academia Brasileira de Ciencias
- 2017
Human aging is characterized by both physical and physiological frailty that profoundly affects the immune system. In this context aging is associated with declines in adaptive and innate immunity… Expand
NADPH oxidase 2 (NOX2): A key target of oxidative stress-mediated platelet activation and thrombosis.
- E. Fuentes, J. Gibbins, L. Holbrook, I. Palomo
- Chemistry, Medicine
- Trends in cardiovascular medicine
- 1 October 2018
Oxidative stress represents an imbalance between the production of reactive oxygen species (ROS) and the cellular antioxidant system. Increased levels of oxidative stress contribute to the… Expand
Mechanisms of endothelial cell protection by hydroxycinnamic acids.
- E. Fuentes, I. Palomo
- Biology, Medicine
- Vascular pharmacology
- 1 December 2014
An endothelial dysfunction generates a proatherogenic environment characterized by stimulating thrombus formation. Epidemiological studies have provided evidence of a protective role of healthy diets… Expand
Extracellular ATP metabolism on vascular endothelial cells: A pathway with pro-thrombotic and anti-thrombotic molecules.
- E. Fuentes, I. Palomo
- Biology, Medicine
- Vascular pharmacology
- 1 December 2015
Vascular endothelial contributes to the metabolism and interconversion of extracellular adenine nucleotides via ecto-ATPase/ADPase (CD39) and ecto-5'nucleotidase (CD73) activities. These enzymes… Expand