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The Pattern of Myometrial Invasion as a Predictor of Lymph Node Metastasis or Extrauterine Disease in Low-grade Endometrial Carcinoma
The purpose of this study was to examine predictors of lymph node (LN) metastases or extrauterine disease (ED) in low-grade (FIGO grade 1 or 2) endometrioid carcinoma (LGEC) in a multi-institutionalExpand
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Variance in the interpretation of cervical biopsy specimens obtained for atypical squamous cells of undetermined significance.
We sought to determine whether the variability in dysplasia rates in cases of atypical squamous cells of undetermined significance (ASCUS) reflects variability in interpretation of cervical biopsyExpand
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Expression of UGT2B7, a UDP-glucuronosyltransferase implicated in the metabolism of 4-hydroxyestrone and all-trans retinoic acid, in normal human breast parenchyma and in invasive and in situ breast
Glucuronidation, mediated by UDP-glucuronosyltransferases (UGTs), affects the actions and disposition of diverse endo- and xenobiotics. In the case of catecholestrogens (CEs), glucuronidation isExpand
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Thyroid Lymphoma: A Single Institution's Experience
BACKGROUND: Primary lymphoma of the thyroid gland is uncommon. METHODS: The tumor registry at the Penn State Milton S. Hershey Medical Center was searched for all patients carrying a diagnosis ofExpand
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Class I alcohol dehydrogenase is highly expressed in normal human mammary epithelium but not in invasive breast cancer: implications for breast carcinogenesis.
Detoxification of ethanol can contribute to oxidative cellular and DNA damage and, thereby, to carcinogenesis. The potential relevance of this to breast carcinogenesis is suggested by evidence thatExpand
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Accuracy and reproducibility of the IDS rapID STR system for species identification of streptococci.
The RapID STR system (Innovative Diagnostic Systems, Inc., Atlanta, Ga.) was evaluated in the identification of 266 streptococci. Organisms included 60 beta-hemolytic streptococci, 71 group D strainsExpand
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An aromatase-producing sex-cord tumor resulting in prepubertal gynecomastia.
GYNECOMASTIA in prepubertal children usually results from an increase in endogenous estrogen production. Estrogen biosynthesis involves the transformation of steroid precursors to androgens and thenExpand
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Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase
Pro-inflammatory cytokines like TNF-α activate sphingosine kinase (SK). Therefore, inhibition of SK is a potential molecular target for the treatment of rheumatoid arthritis.AimsThe primary goal ofExpand
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CD10‐positive myxofibrosarcomas: a pitfall in the differential diagnosis of atypical fibroxanthoma
CD10 is now commonly used to differentiate atypical fibroxanthoma (AFX) from melanoma, spindle cell and dedifferentiated variants of squamous cell carcinoma and leiomyosarcoma. However, we haveExpand
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Clear cell cribriform hyperplasia of the prostate. Immunohistochemical and DNA flow cytometric study.
Clear cell cribriform hyperplasia (CCCH) of the prostate is an unusual form of benign prostatic hyperplasia characterized by a nodular proliferation of clear cells with small, uniform nuclei. TheExpand
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