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Route of passive ion permeation in epithelia.
“Tight junctions” between cells in some epithelia actually provide the main route of passive ion permeation. The degree of junctional tightness may underlie important functional differences betweenExpand
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The route of passive ion movement through the epithelium ofNecturus gallbladder
  • E. Frömter
  • Chemistry, Medicine
  • The Journal of Membrane Biology
  • 2005
SummaryElectrophysiological experiments were performed onNecturus gallbladder to determine whether the main route of passive ion flow was via the cells or via a paracellular shunt path. In the firstExpand
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Pathways of NH3/NH4+ permeation across Xenopus laevis oocyte cell membrane
While acid loading with extracellular NH4Cl solutions usually first alkalinizes the cells through NH3 influx, and acidifies only when NH4Cl is removed, Xenopus oocytes became immediately acidic uponExpand
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A new double-barrelled, ionophore-based microelectrode for chloride ions
A new Cl− selective microelectrode based on the ionophore 5,10,15,20-tetraphenyl-21H,23H-porphin manganese(III) chloride is presented which discriminates better against HCO3− and several organicExpand
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Phenomenologic description of Na+, Cl− and HCO3− absorption from proximal tubules of the rat kidney
SummaryProximal tubules of the rat kidney were perfused in vivo with NaCl-NaHCO3 Ringer's solution and the net rates of fluid absorption from Gertz shrinking drops were measured as well as theExpand
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Hypertonicity activates nonselective cation channels in mouse cortical collecting duct cells.
We investigated the effect of cell shrinkage on whole-cell currents of M-1 mouse cortical collecting duct cells. Addition of 100 mM sucrose to an isotonic NaCl bath solution induced cell shrinkageExpand
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Basolateral proteinase‐activated receptor (PAR‐2) induces chloride secretion in M‐1 mouse renal cortical collecting duct cells
1 Using RT‐PCR, Northern blot analysis, and immunocytochemistry, we confirmed renal expression of proteinase‐activated receptor (PAR‐2) and demonstrated its presence in native renal epithelial and inExpand
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The renal Na-HCO3-cotransporter expressed in Xenopuslaevis oocytes: change in stoichiometry in response to elevation of cytosolic Ca2+ concentration
Abstract. The Na+-HCO3– cotransporter of rat kidney (rkNBC) was expressed in Xenopuslaevis oocytes to test whether cytosolic Ca2+ ([Ca2+]i) affects the cotransport stoichiometry. The current/voltageExpand
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A Calcium-activated and nucleotide-sensitive nonselective cation channel in M-1 mouse cortical collecting duct cells
We recently reported that M-1 mouse cortical collecting duct cells show nonselective cation (NSC) channel activity (Proc. Natl. Acad. Sci. USA89:10262–10266, 1992). In this study, we furtherExpand
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The renal Na-HCO3-cotransporter expressed in Xenopus laevis oocytes: inhibition by tenidap and benzamil and effect of temperature on transport rate and stoichiometry
Abstract. In the present experiments we expressed the rat kidney Na+-HCO3– cotransporter (rkNBC) in Xenopus laevis oocytes to reinvestigate the flux coupling ratio under improved measuringExpand
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