• Publications
  • Influence
Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study
Flavonoids are polyphenolic antioxidants naturally present in vegetables, fruits, and beverages such as tea and wine. In vitro, flavonoids inhibit oxidation of low-density lipoprotein and reduceExpand
  • 4,216
  • 81
Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men.
Atherosclerosis and thrombosis may lead to cognitive impairment through cerebral infarcts or white matter hyperintensities. Oxidative stress is now seen as a major contributor to the process ofExpand
  • 422
  • 29
  • PDF
Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study
BACKGROUND Evidence on the relation between trans fatty acid intake and coronary heart disease is limited. We investigated this relation in a Dutch population with a fairly high trans fatty acidExpand
  • 481
  • 23
  • PDF
Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly Study.
BACKGROUND Epidemiologic studies suggest that tea consumption may reduce the risk of cardiovascular diseases, but results are inconsistent. Catechins, which belong to the flavonoid family, are theExpand
  • 333
  • 20
Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study.
BACKGROUND Epidemiological studies suggested that consumption of fruit and vegetables may protect against stroke. The hypothesis that dietary antioxidant vitamins and flavonoids account for thisExpand
  • 857
  • 18
Dietary Factors Determining Diabetes and Impaired Glucose Tolerance: A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study
OBJECTIVE To investigate the role of diet as a predictor of glucose intolerance and non-insulin-dependent diabetes mellitus (NIDDM). RESEARCH DESIGN AND METHODS At the 30-year follow-up survey of theExpand
  • 528
  • 16
The amount and type of dairy product intake and incident type 2 diabetes: results from the EPIC-InterAct Study.
BACKGROUND Dairy product intake may be inversely associated with risk of type 2 diabetes, but the evidence is inconclusive for total dairy products and sparse for types of dairy products. OBJECTIVEExpand
  • 176
  • 16
Cocoa intake, blood pressure, and cardiovascular mortality: the Zutphen Elderly Study.
BACKGROUND Small, short-term, intervention studies indicate that cocoa-containing foods improve endothelial function and reduce blood pressure. We studied whether habitual cocoa intake wasExpand
  • 399
  • 15
  • PDF
Performance of a predictive model to identify undiagnosed diabetes in a health care setting.
OBJECTIVE To develop a predictive model to identify individuals with an increased risk for undiagnosed diabetes, allowing for the availability of information within the health care system. RESEARCHExpand
  • 176
  • 13
Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria.
BACKGROUND New diagnostic criteria for diabetes based on fasting blood glucose (FBG) level were approved by the American Diabetes Association. The impact of using FBG only has not been evaluatedExpand
  • 1,284
  • 12