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Catalytic C-H bond functionalization with palladiumII: aerobic oxidative annulations of indoles.
A palladium-catalyzed aerobic oxidative annulation of indoles is described. We have demonstrated that a variety of factors influence these cyclizations, and in particular the electronic nature of theExpand
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C-H Bond Functionalizations with Palladium(II): Intramolecular Oxidative Annulations of Arenes.
Oxidative annulations for the synthesis of carbocycles were developed using a catalytic palladium(II) system. Indoles with pendant olefin tethers were oxidatively cyclized to form annulated products.Expand
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Photooxidizing chromium catalysts for promoting radical cation cycloadditions.
The photooxidizing capabilities of selected Cr(III) complexes for promoting radical cation cycloadditions are described. These complexes have sufficiently long-lived excited states to oxidizeExpand
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Engineering a bacterial platform for total biosynthesis of caffeic acid derived phenethyl esters and amides.
Caffeic acid has been widely recognized as a versatile pharmacophore for synthesis of new chemical entities, among which caffeic acid derived phenethyl esters and amides are the mostExpand
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Lewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum Carbene.
A variety of substituted indoles and benzofurans are accessed via a platinum catalyzed annulation and vinylogous addition of enol nucleophiles. Several β-dicarbonyl compounds participate in theExpand
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The palladium-catalyzed oxidative kinetic resolution of secondary alcohols with molecular oxygen.
The oxidation of secondary alcohols is one of the most common and well-studied reactions in chemistry. Although excellent catalytic enantioselective methods exist for a variety of oxidationExpand
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Palladium-catalyzed oxidative wacker cyclizations in nonpolar organic solvents with molecular oxygen: a stepping stone to asymmetric aerobic cyclizations.
A variety of Pd-catalyzed oxidative nucleophile/alkene cyclizations proceeds in excellent yield under simple aerobic conditions in nonpolar media (Pd catalyst, pyridine, and O_2 in toluene).Expand
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Direct oxidative Heck cyclizations: intramolecular Fujiwara-Moritani arylations for the synthesis of functionalized benzofurans and dihydrobenzofurans.
No extra functionalization step is required for palladium(II)-catalyzed oxidative carbocyclizations like that shown, which provide highly substituted benzofuran and dihydrobenzofuran derivatives byExpand
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