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The Genoa 2005 outbreak. Determination of putative palytoxin in Mediterranean Ostreopsis ovata by a new liquid chromatography tandem mass spectrometry method.
It is suggested that putative palytoxin was the causative agent responsible for patients' symptoms and demonstrated for the first time the presence of such a toxin in Italian waters.
Modern Alkaloids : Structure, Isolation, Synthesis and Biology
The structure and pharmacological properties of Alkaloid-like Compounds and their applications in Clinical Use or in Clinical Trials are described.
Comparative growth and toxin profile of cultured Ostreopsis ovata from the Tyrrhenian and Adriatic Seas.
Yessotoxin in mussels of the northern Adriatic Sea.
Complex palytoxin-like profile of Ostreopsis ovata. Identification of four new ovatoxins by high-resolution liquid chromatography/mass spectrometry.
A quantitative study of the O. ovata culture extract indicated that the whole of the new ovatoxins represents about 46% of the total toxin content and, thus, their presence has to be taken into account when LC/MS-based monitoring programs of either plankton or contaminated seafood are carried out.
Isolation and structure elucidation of ovatoxin-a, the major toxin produced by Ostreopsis ovata.
The present paper reports on the isolation, NMR-based structural determination, and preliminary mouse lethality evaluation of ovatoxin-a, the major toxic compound contained in O. cf.
Bromopyrrole Alkaloids as Lead Compounds against Protozoan Parasites
Results indicate longamide B and dibromopalau’amine (11) to be promising trypanocidal and antileishmanial agents, while dispacamide B (3) and spongiacidin B (6) emerge as antimalarial lead compounds.