E. Fan

Publications396
h-index69
Citations29,079
Highly Influential Citations1,291
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Acute respiratory distress syndrome: the Berlin Definition.
TLDR
The updated and revised Berlin Definition for ARDS addresses a number of the limitations of the AECC definition and may serve as a model to create more accurate, evidence-based, critical illness syndrome definitions and to better inform clinical care, research, and health services planning.
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Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.
TLDR
Clinician recognition of ARDS was associated with higher PEEP, greater use of neuromuscular blockade, and prone positioning, which indicates the potential for improvement in the management of patients with ARDS.
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Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19)
TLDR
The Surviving Sepsis Campaign CO VID-19 panel issued several recommendations to help support healthcare workers caring for critically ill ICU patients with COVID-19, and will provide new recommendations in further releases of these guidelines.
View on Springer
The Berlin definition of ARDS: an expanded rationale, justification, and supplementary material
TLDR
This panel addressed some of the limitations of the prior ARDS definition by incorporating current data, physiologic concepts, and clinical trials results to develop the Berlin definition, which should facilitate case recognition and better match treatment options to severity in both research trials and clinical practice.
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Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome
TLDR
Among patients with very severe ARDS, 60‐day mortality was not significantly lower with ECMO than with a strategy of conventional mechanical ventilation that included ECMO as rescue therapy, and fewer cases of ischemic stroke.
View on Wolters Kluwer
An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute…
TLDR
Clinicians managing patients with ARDS should personalize decisions for their patients, particularly regarding the conditional recommendations in this guideline, which is strong for mechanical ventilation using lower tidal volumes and lower inspiratory pressures.
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Acute Respiratory Distress Syndrome: Advances in Diagnosis and Treatment
TLDR
The Berlin definition of acute respiratory distress syndrome addressed limitations of the American-European Consensus Conference definition, but poor reliability of some criteria may contribute to underrecognition by clinicians.
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Early physical medicine and rehabilitation for patients with acute respiratory failure: a quality improvement project.
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Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry
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Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study
TLDR
NIV was used in 15% of patients with ARDS, irrespective of severity category, and NIV seems to be associated with higher ICU mortality in patients with a PaO2/FiO2 lower than 150 mm Hg.
View on Wolters Kluwer
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