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In vivo antimalarial activity of the crude leaf extract and solvent fractions of Croton macrostachyus Hocsht. (Euphorbiaceae) against Plasmodium berghei in mice
BackgroundThe issue of resistance in malarial infection makes development of novel drugs a necessity. An alternative source for discovering such drugs is natural products. Croton macrostachyus H.Expand
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Highly active antiretroviral therapy adherence and its determinants in selected hospitals from south and central Ethiopia.
OBJECTIVE To determine the adherence rate and its determinants among people living with HIV/AIDS on highly active antiretroviral therapy (HAART) in selected governmental hospitals from central andExpand
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Evaluation of the diuretic and analgesic activities of the rhizomes of Rumex abyssinicus Jacq in mice.
AIM OF THE STUDY Rumex abyssinicus Jacq (Polygonaceae) has been used traditionally for treatment of hypertension, inflammatory and painful conditions in Ethiopia. The present study aimed to evaluateExpand
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Evaluation of in vivo antihypertensive and in vitro vasodepressor activities of the leaf extract of Syzygium guineense (Willd) D.C.
The aim of this work was to evaluate the antihypertensive activity of the hydroalcohol extract of the leaves of Syzygium guineense (Willd) D.C. (Myrtaceae) in a 1-kidney-1-clip rat model and itsExpand
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Evaluation of the effects of 80% methanolic leaf extract of Caylusea abyssinica (fresen.) fisch. & Mey. on glucose handling in normal, glucose loaded and diabetic rodents
BackgroundThe leaves of Caylusea abyssinica (fresen.) Fisch. & Mey. (Resedaceae), a plant widely distributed in East African countries, have been used for management of diabetes mellitus in EthiopianExpand
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Evaluation of the antidiarrheal activity of the leaf extracts of Myrtus communis Linn (Myrtaceae) in mice model
BackgroundMyrtus communis L. has a folkloric repute for the management of diarrhea and dysentery in different parts of the world. However, the safety and efficacy of the leaf extract have not beenExpand
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Evaluation of wound healing and anti-inflammatory activity of the rhizomes of Rumex abyssinicus J. (Polygonaceae) in mice
BackgroundRumex abyssinicus Jacq (Polygonaceae) is widely used in Ethiopia for treatment of wound and other diseases. Although reports are available in the literature on some of the claimedExpand
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Reproductive parameters are differentially altered following subchronic administration of Catha edulis F. (Khat) extract and cathinone in male rats.
AIMS OF THE STUDY Controversy surrounds on the effect of khat, a widely chewed herb for its stimulant effect on sexuality. This study investigated the effect of fresh Catha edulis F. (Khat) extract,Expand
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Antihypertensive activity of 80% methanol seed extract of Calpurnia aurea (Ait.) Benth. subsp. aurea (Fabaceae) is mediated through calcium antagonism induced vasodilation.
ETHNOPHARMACOLOGICAL RELEVANCE Calpurnia aurea (Ait.) Benth. subsp. aurea (CASA) (Fabaceae) seeds are used to treat hypertension in Ethiopian folklore medicine, particularly by Shinasha, Agew-awi andExpand
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Quality of life of people living with HIV/AIDS and on highly active antiretroviral therapy in Ethiopia
The Amharic version of the Short Form-36 Health Survey (SF-36) was used to measure quality of life among patients on highly active antiretroviral therapy (HAART) at selected governmental hospitals inExpand
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