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- Publications
- Influence
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
- B. Keele, E. Giorgi, +34 authors G. Shaw
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 27 May 2008
The precise identification of the HIV-1 envelope glycoprotein (Env) responsible for productive clinical infection could be instrumental in elucidating the molecular basis of HIV-1 transmission and in… Expand
Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction
- L. Trautmann, L. Janbazian, +10 authors R. Sekaly
- Biology, Medicine
- Nature Medicine
- 20 August 2006
The engagement of programmed death 1 (PD-1) to its ligands, PD-L1 and PD-L2, inhibits proliferation and cytokine production mediated by antibodies to CD3 (refs. 5,6,7). Blocking the PD-1–PD-L1… Expand
Human Bocaviruses Are Highly Diverse, Dispersed, Recombination Prone, and Prevalent in Enteric Infections
- A. Kapoor, P. Simmonds, +11 authors E. Delwart
- Biology, Medicine
- The Journal of infectious diseases
- 1 June 2010
Abstract A new species of parvovirus, tentatively named human bocavirus 4 (HBoV4), was genetically characterized. Among 641 feces samples obtained from children and adults, the most commonly detected… Expand
Multiple Diverse Circoviruses Infect Farm Animals and Are Commonly Found in Human and Chimpanzee Feces
- L. Li, A. Kapoor, +15 authors E. Delwart
- Biology, Medicine
- Journal of Virology
- 9 December 2009
ABSTRACT Circoviruses are known to infect birds and pigs and can cause a wide range of severe symptoms with significant economic impact. Using viral metagenomics, we identified circovirus-like DNA… Expand
Detection of a novel circovirus PCV3 in pigs with cardiac and multi-systemic inflammation
- T. Phan, F. Giannitti, +7 authors E. Delwart
- Biology, Medicine
- Virology Journal
- 11 November 2016
BackgroundPorcine circovirus 2 causes different clinical syndromes resulting in a significant economic loss in the pork industry. Three pigs with unexplained cardiac and multi-organ inflammation that… Expand
Bat Guano Virome: Predominance of Dietary Viruses from Insects and Plants plus Novel Mammalian Viruses
- L. Li, J. G. Victoria, +4 authors E. Delwart
- Biology, Medicine
- Journal of Virology
- 12 May 2010
ABSTRACT Bats are hosts to a variety of viruses capable of zoonotic transmissions. Because of increased contact between bats, humans, and other animal species, the possibility exists for further… Expand
New DNA Viruses Identified in Patients with Acute Viral Infection Syndrome
- M. S. Jones, A. Kapoor, V. Lukashov, P. Simmonds, F. Hecht, E. Delwart
- Biology, Medicine
- Journal of Virology
- 1 July 2005
ABSTRACT A sequence-independent PCR amplification method was used to identify viral nucleic acids in the plasma samples of 25 individuals presenting with symptoms of acute viral infection following… Expand
A newly identified bocavirus species in human stool.
- A. Kapoor, Elizabeth Slikas, +8 authors E. Delwart
- Biology, Medicine
- The Journal of infectious diseases
- 15 January 2009
Viral metagenomic analysis was used to identify a previously uncharacterized parvovirus species, "HBoV2," whose closest phylogenetic relative is the human bocavirus (HBoV). HBoV2 has a genomic… Expand
The Fecal Virome of Pigs on a High-Density Farm †
- Tongling Shan, L. Li, P. Simmonds, C. Wang, A. Moeser, E. Delwart
- Biology, Medicine
- Journal of Virology
- 7 September 2011
ABSTRACT Swine are an important source of proteins worldwide but are subject to frequent viral outbreaks and numerous infections capable of infecting humans. Modern farming conditions may also… Expand
Multiple novel astrovirus species in human stool.
- A. Kapoor, L. Li, +5 authors E. Delwart
- Biology, Medicine
- The Journal of general virology
- 1 December 2009
Diarrhoea remains a significant cause of morbidity and mortality in developing countries where numerous cases remain without identified aetiology. Astroviruses are a recently identified cause of… Expand