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Thyroid dysfunction and autoantibodies in early pregnancy are associated with increased risk of gestational diabetes and adverse birth outcomes.
- P. Karakosta, Dimitris Alegakis, +7 authors L. Chatzi
- The Journal of clinical endocrinology and…
- 26 September 2012
CONTEXT Maternal thyroid dysfunction, especially in early pregnancy, may lead to pregnancy complications and adverse birth outcomes. Few population-based prospective studies have evaluated these… Expand
Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action
- M. Kampa, Vassilia-Ismini Alexaki, +9 authors E. Castanas
- Chemistry, Medicine
- Breast Cancer Research
- 15 December 2003
IntroductionThe oncoprotective role of food-derived polyphenol antioxidants has been described but the implicated mechanisms are not yet clear. In addition to polyphenols, phenolic acids, found at… Expand
[Corticotropin releasing factor].
The search for a neurohormone specifically controlling ACTH secretion resulted in the discovery of the corticotropin-releasing factor (CRF). This factor, located mainly in a… Expand
Potent inhibitory action of red wine polyphenols on human breast cancer cells
- A. Damianaki, E. Bakogeorgou, +7 authors E. Castanas
- Biology, Medicine
- Journal of cellular biochemistry
- 1 September 2000
Breast cancer (one of the most common malignancy in Western societies), as well as esophagus, stomach, lung, bladder, and prostate cancer, depend on environmental factors and diet for growth and… Expand
Human health effects of air pollution.
Hazardous chemicals escape to the environment by a number of natural and/or anthropogenic activities and may cause adverse effects on human health and the environment. Increased combustion of fossil… Expand
Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins.
- I. Charalampopoulos, C. Tsatsanis, +4 authors A. Gravanis
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 25 May 2004
The neuroactive steroids dehydroepiandrosterone (DHEA), its sulfate ester DHEA sulfate (DHEAS), and allopregnanolone (Allo), produced by the CNS and the adrenals, appear to exert a protective effect… Expand
Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation.
- G. Notas, Artemissia-Phoebe Nifli, M. Kampa, J. Vercauteren, E. Kouroumalis, E. Castanas
- Biology, Medicine
- Biochimica et biophysica acta
- 1 November 2006
The stilbene resveratrol exerts antiproliferative and proapoptotic actions on a number of different cancer cell lines, through diverse mechanisms, including antioxidant effects, enzyme, growth factor… Expand
A new automated method for the determination of the Total Antioxidant Capacity (TAC) of human plasma, based on the crocin bleaching assay
- M. Kampa, Anastasia Nistikaki, V. Tsaousis, N. Maliaraki, G. Notas, E. Castanas
- BMC clinical pathology
- 28 August 2002
BackgroundAntioxidant molecules, which scavenge free radical species to prevent or delay oxidative damage of important macromolecules, membrane lipids and lipoproteins, are prevalent in plasma and… Expand
Decreased Total and Corrected Antioxidant Capacity in Patients with Inflammatory Bowel Disease
- I. Koutroubakis, N. Malliaraki, P. Dimoulios, K. Karmiris, E. Castanas, E. Kouroumalis
- Digestive Diseases and Sciences
- 1 September 2004
Oxidative stress and depletion of antioxidants may play a key role in the pathogenesis of inflammatory bowel disease (IBD)-related intestinal damage. A new automated assay for the determination of… Expand
Leptin levels in cord blood and anthropometric measures at birth: a systematic review and meta-analysis.
- P. Karakosta, L. Chatzi, E. Plana, A. Margioris, E. Castanas, M. Kogevinas
- Paediatric and perinatal epidemiology
- 1 March 2011
The role of intrauterine environment in the development of obesity is increasingly recognised. Adipokines and specifically leptin have been examined as potential biomarkers predicting early… Expand