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Gene frequencies of the HPA‐15 (Gov) platelet alloantigen system in Brazilians
Summary.  The HPA‐15 (Gov) alloantigen is a biallelic co‐dominant system on human platelets, and its allele HPA‐15a and HPA‐15b differ by an A→C single nucleotide polymorphism at nucleotide 2108 ofExpand
Urinary iron excretion induced by intravenous infusion of deferoxamine in beta-thalassemia homozygous patients.
TLDR
Noninvasive methods to evaluate the severity of iron overload in transfusion-dependent beta-thalassemia and the efficiency of intensive intravenous therapy as an additional tool for the treatment of iron-overloaded patients are identified. Expand
Molecular Basis of KELnull Phenotype in Brazilians
TLDR
This report represents the first study of K₀ molecular basis performed in Amerindian-Caucasian descendants from South America. Expand
Molecular studies reveal a concordant KEL genotyping between patients with hemoglobinopathies and blood donors in São Paulo City, Brazil
Kell is the most important blood group system after ABO and Rh because all frequently occurring Kell-specific antibodies must be considered clinically significant. The highly immunogenic KellExpand
Anti-KEL7 (anti-Js(b)) alloimmunization diagnostic supported by molecular KEL*6,7 typing in a pregnant woman with previous intrauterine deaths.
TLDR
A case of anti-KEL7 alloimmunization detected in a pregnant woman who had an obstetric previous history of four miscarriages and one stillborn is reported, using a KEL*6,7 genotyping method as an alternative tool to contribute with the identification of the alloantibody origin. Expand
Novel Kelnull Allele Detected In a Brazilian Woman with the Kell Null Phenotype.
TLDR
A 59-year-old Caucasian-Amerindian descent woman (proband) from Northeast Brazil who showed an antibody that reacted against high-prevalence RBC antigens during a pre-transfusion evaluation for orthopedic surgery is investigated. Expand
Frequencies of KEL*29 (KALT) and KEL*30 (KTIM) alleles in blood donors and patients with hemoglobinopathies in Brazil
TLDR
The data suggest that the KEL29 and KEL30 antigens have little clinical impact, because the alloimmunization by these antIGens is probably a very rare event. Expand
Novel IVS6‐13C>T mutation recognized as a cause of discrepancy between phenotyping and genotyping in KEL*3,4 polymorphism identification
TLDR
Although plasma levels of rituximab are low or undetectable 4 months after its infusion, a 6-month frequency administration could be enough to achieve the long-term B-cell depletion necessary to maintain the remission. Expand