• Publications
  • Influence
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals
The role of skeletal muscle in nonshivering thermogenesis (NST) is not well understood. Here we show that sarcolipin (Sln), a newly identified regulator of the sarco/endoplasmic reticulum Ca2+-ATPaseExpand
  • 360
  • 29
Estrogen effect on post-exercise skeletal muscle neutrophil infiltration and calpain activity.
We hypothesized that estrogen administration would attenuate skeletal muscle neutrophil infiltration, indices of muscle membrane disruption, and muscle calpain activity shortly after the terminationExpand
  • 122
  • 12
Ca2+ dysregulation in Ryr1I4895T/wt mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods
Ryr1I4895T/wt (IT/+) mice express a knockin mutation corresponding to the human I4898T EC-uncoupling mutation in the type 1 ryanodine receptor/Ca2+ release channel (RyR1), which causes a severe formExpand
  • 69
  • 8
  • PDF
Serial effects of high-resistance and prolonged endurance training on Na+-K+ pump concentration and enzymatic activities in human vastus lateralis.
The purpose of this study was to compare two contrasting training models, namely high-resistance training and prolonged submaximal training on the expression of Na+-K+ ATPase and changes in theExpand
  • 73
  • 7
Muscle fiber type-specific response of Hsp70 expression in human quadriceps following acute isometric exercise.
To investigate the time course of fiber type-specific heat shock protein 70 (Hsp70) expression in human skeletal muscle after acute exercise, 10 untrained male volunteers performed single-leggedExpand
  • 65
  • 7
  • PDF
Ablation of sarcolipin decreases the energy requirements for Ca2+ transport by sarco(endo)plasmic reticulum Ca2+‐ATPases in resting skeletal muscle
The purpose of this study was to examine the effects of sarcolipin (SLN) on sarco(endo) plasmic reticulum Ca2+‐ATPase (SERCA pump) energetics in vivo and resting skeletal muscle metabolic rate. UsingExpand
  • 39
  • 6
Effects of ovarian sex hormones and downhill running on fiber-type-specific HSP70 expression in rat soleus.
This study examined the influence of the ovarian sex hormones, estrogen and progesterone, on the fiber-type-specific response of the inducible 70-kDa heat shock protein (HSP70) to damaging exerciseExpand
  • 44
  • 5
  • PDF
ATP Consumption by Sarcoplasmic Reticulum Ca2+ Pumps Accounts for 40-50% of Resting Metabolic Rate in Mouse Fast and Slow Twitch Skeletal Muscle
The main purpose of this study was to directly quantify the relative contribution of Ca2+ cycling to resting metabolic rate in mouse fast (extensor digitorum longus, EDL) and slow (soleus) twitchExpand
  • 80
  • 3
  • PDF
Organization of metabolic pathways in vastus lateralis of patients with chronic obstructive pulmonary disease.
The objective of this study was to determine whether patients with chronic obstructive lung disease (COPD) display differences in organization of the metabolic pathways and segments involved inExpand
  • 44
  • 3
Co-Expression of SERCA Isoforms, Phospholamban and Sarcolipin in Human Skeletal Muscle Fibers
Sarcolipin (SLN) and phospholamban (PLN) inhibit the activity of sarco(endo)plasmic reticulum Ca2+-ATPases (SERCAs) by reducing their apparent affinity for Ca2+. A ternary complex between SLN, PLN,Expand
  • 59
  • 3
  • PDF