E. Blum

Publications18
h-index10
Citations570
Highly Influential Citations21
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Polyphosphate kinase is a component of the Escherichia coli RNA degradosome
The Escherichia coli degradosome is a multienzyme complex with four major protein components: the endoribonuclease RNase E, the exoribonuclease PNPase, the RNA helicase RhlB and enolase. The first… Expand
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Antimicrobial susceptibility of staphylococci isolated from otitis externa in dogs
Samples were obtained from 65 unmedicated adult dogs, processed for isolation of Staphylococcus species and tested for susceptibility to penicillin G, gentamicin, oxacillin, tetracycline,… Expand
  • 91
  • 6
Polyadenylation Promotes Degradation of 3′-Structured RNA by theEscherichia coli mRNA Degradosome in Vitro *
Polyadenylation contributes to the destabilization of bacterial mRNA. We have investigated the role of polyadenylation in the degradation of RNA by the purifiedEscherichia coli degradosome in vitro.… Expand
  • 110
  • 2
Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis.
A library of trisubstituted oxazoles, thiazoles, imidazoles (1,2,4- and 2,4,5-substituted) and imidazo[1,2-b]pyridines was prepared and evaluated in vitro as p38alpha inhibitors and in vivo in… Expand
  • 62
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Association of mitogen-activated protein kinases with microtubules in mouse macrophages
Taxol, a microtubule-binding diterpene, mimics many effects of lipopolysaccharide (LPS) on mouse macrophages. The LPS-mimetic effects of taxol appear to be under the same genetic control as responses… Expand
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Pyrazoloheteroaryls: novel p38alpha MAP kinase inhibiting scaffolds with oral activity.
A test library with three novel p38alpha inhibitory scaffolds and a narrow set of substituents was prepared. Appropriate combination of substituent and scaffold generated potent p38alpha inhibitors,… Expand
  • 59
SAR of benzoylpyridines and benzophenones as p38alpha MAP kinase inhibitors with oral activity.
Benzoylpyridines and benzophenones were synthesized and evaluated in vitro as p38alpha inhibitors and in vivo in several models of rheumatoid arthritis. Oral activity was found to depend upon… Expand
  • 27
Die Querschnittsbeziehungen zwischen Stamm und Ästen im Arteriensystem
  • E. Blum
  • Physics
  • Pflüger's Archiv für die gesamte Physiologie des…
  • 1 December 1919
ZusammenfassungEs wird versucht, durch Anwendung einer neuen Methode Aufschluss über das Verhältnis zwischen Gesamtquerschnitt der Arterienäste zum Querschnitt des zugehörigen Stammes zu erhalten.… Expand
  • 3
Practical low-noise quasiparticle receiver for 80-100 GHz
We have tested a heterodyne receiver for millimetre-wave radio astronomy, which uses a quasiparticle mixer with junctions of Pb/Bi/In-oxide-Pb/Bi. A receiver noise temperature of around 100 K double… Expand
  • 18
Low-noise 140-170 GHz heterodyne receiver using quasiparticle tunnel junctions
Laboratory tests have been made using single quasiparticle tunnel junctions as the nonlinear element for mixing in a heterodyne receiver. Double-sideband receiver noise temperatures of l00±10 K are… Expand
  • 13