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MAPK and JNK transduction pathways can phosphorylate Sp1 to activate the uPA minimal promoter element and endogenous gene transcription.
Two upstream regions of the human urokinase (uPA) gene regulate its transcription: the minimal promoter (MP) and the enhancer element. The activity of the minimal promoter is essential for basal uPA… Expand
Corticocancellous porcine bone in the healing of human extraction sockets: combining histomorphometry with osteoblast gene expression profiles in vivo.
- R. Crespi, P. Capparé, G. Romanos, E. Mariani, E. Benasciutti, E. Gherlone
- The International journal of oral & maxillofacial…
- 1 July 2011
PURPOSE Different graft materials have been proposed to minimize the collapse of alveolar bone after tooth extraction. The aim of this study was to examine the use of porcine bone graft in fresh… Expand
MHC Class II Transactivator Is an In Vivo Regulator of Osteoclast Differentiation and Bone Homeostasis Co‐opted From Adaptive Immunity
- E. Benasciutti, E. Mariani, +16 authors S. Cenci
- Medicine, Biology
- Journal of bone and mineral research : the…
- 1 February 2014
The molecular networks controlling bone homeostasis are not fully understood. The common evolution of bone and adaptive immunity encourages the investigation of shared regulatory circuits. MHC Class… Expand
Magnesium-enriched hydroxyapatite versus autologous bone in maxillary sinus grafting: combining histomorphometry with osteoblast gene expression profiles ex vivo.
- R. Crespi, E. Mariani, E. Benasciutti, P. Capparé, S. Cenci, E. Gherlone
- Journal of periodontology
- 1 April 2009
BACKGROUND Many biomaterials are proposed for sinus floor lifting and grafting in the posterior maxilla for insufficient bone volume (BV). The aim of this study was to compare the use of… Expand
Phospholipase C Gamma 2 Is Critical for Development of a Murine Model of Inflammatory Arthritis by Affecting Actin Dynamics in Dendritic Cells
- V. Cremasco, E. Benasciutti, M. Cella, M. Kisseleva, M. Croke, R. Faccio
- Medicine, Biology
- PloS one
- 27 January 2010
Background Dendritic cells (DCs) are highly specialized cells, which capture antigen in peripheral tissues and migrate to lymph nodes, where they dynamically interact with and activate T cells. Both… Expand
MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity
Characterization of different in vitro culture conditions to induce a fibro-chondrogenic differentiation of swine adipose-derived stem cells.
- I. Tessaro, A. Di Giancamillo, +4 authors G. Peretti
- Journal of biological regulators and homeostatic…
- 1 November 2018
Meniscus repair is still a challenge for orthopaedic surgeons as this tissue has a scarce healing potential due to the limited vascularization and to the lack of progenitor cells. Lately, several… Expand
CIITA: A novel regulator of osteoclastogenesis and bone microarchitecture controlled by estrogen in vivo
N-cadherin/LRP5 interaction, indicating that this interaction implies the last 62 AA of N-cadherin. Consistent with this finding, transfection with Δ62 N-cadherin restored the defective β-catenin… Expand
Mouse genetic models reveal MHC Class II Transactivator as a novel regulator of osteoclastogenesis and bone homeostasis co-opted from adaptive immunity