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Oleuropein Prevents Neuronal Death, Mitigates Mitochondrial Superoxide Production and Modulates Autophagy in a Dopaminergic Cellular Model
Parkinson’s disease (PD) is a progressive neurodegenerative disorder, primarily affecting dopaminergic neurons in the substantia nigra. There is currently no cure for PD and present medications aimExpand
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Morphological effects induced by Cucurbitacin E on ovarian cancer cells in vitro
Objective: To study the effects of Cucurbitacin E, extracted from Ecballium elaterium L. A.Rich. on ovarian cancer cell lines in vitro . Materials and methods: Human ovarian cancer cells (OV_95_CC3)Expand
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Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium.
The immunomodulatory effect of cucurbitacin E, extracted from Ecballium elaterium, was tested on peripheral human lymphocytes. These lymphocytes were co-cultured with cancer cells and an interestingExpand
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The Effects of Cucurbitacin E on Two Lymphocyte Models
Cucurbitacin E (CuE), like other cucurbitacins, is a potential anti-neoplastic agent. The aim of the present study was to investigate the in vitro effects of CuE on phytohaemagglutininExpand
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Effects of Ephedrine and Ephedra fragilis Crude Extracts on Human Peripheral Lymphocytes
Ephedra fragilis Desf. (Ephedraceae), a locally cultivated medicinal plant, is a source of ephedrine and pseudoephedrine, two important alkaloids, which have long played an important pharmacologicalExpand
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The cultivation and cucurbitacin content of Ecballium elaterium (L.) A. rich
Introduction: Although Ecballium elaterium (L.) A. Rich., is considered as a minor crop in the Cucurbitaceae family. However, its medicinal virtues (3, 8) and its resistance to pests and diseases (6,Expand
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Study on Seasonal Variation on the Content of Cucurbitacin of Various Vegetative Parts of Trichosanthes cucumerina L. var. cucumerina
The total cucurbitacin content produced in the different parts of T. cucumerina L. var. cucumerina viz., fruit, stem and leaves with time and temperature was studied during the year 2007-08. TheExpand
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Use of Extracts from Squirting Cucumber ( Ecballium elaterium ) Seeds in Health
Publisher Summary This chapter summarizes the nutritional benefits of squirting cucumber extracts. The fruit is considered to be a source of pharmacologically active metabolites. ImportantExpand
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Cucurbitacin E Has Neuroprotective Properties and Autophagic Modulating Activities on Dopaminergic Neurons
Natural molecules are under intensive study for their potential as preventive and/or adjuvant therapies for neurodegenerative disorders such as Parkinson's disease (PD). We evaluated theExpand
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Cucurbitacin E, An Experimental Lead Triterpenoid with Anticancer, Immunomodulatory and Novel Effects Against Degenerative Diseases. A Mini-Review.
A growing number of studies have revealed that natural molecules own interesting antioxidant and anti-apoptotic properties in cell culture as well as in animal models of human diseases such asExpand
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