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Clinical and pathologic characteristics of dilated cardiomyopathy in hemodialysis patients.
BACKGROUND Some dialysis patients have impaired left ventricular (LV) function without coronary artery disease. The pathologic changes and prognoses of these patients have not been well described. … Expand
Thrombomodulin Is a Clock-controlled Gene in Vascular Endothelial Cells*
- N. Takeda, K. Maemura, +9 authors R. Nagai
- Medicine, Biology
- Journal of Biological Chemistry
- 9 November 2007
Cardiovascular diseases are closely related to circadian rhythm, which is under the control of an internal biological clock mechanism. Although a biological clock exists not only in the hypothalamus… Expand
Brief Report: Takayasu Arteritis and Ulcerative Colitis: High Rate of Co‐Occurrence and Genetic Overlap
Takayasu arteritis (TAK) is a systemic vasculitis affecting large arteries and large branches of the aorta. Ulcerative colitis (UC) is a prevalent autoimmune colitis. Since TAK and UC share… Expand
The Relationship between Vascular Function and the Autonomic Nervous System.
Endothelial dysfunction and autonomic nervous system dysfunction are both risk factors for atherosclerosis. There is evidence demonstrating that there is a close interrelationship between these two… Expand
VEGF‐A induces its negative regulator, soluble form of VEGFR‐1, by modulating its alternative splicing
Vascular endothelial growth factor‐A (VEGF‐A) is one of the major angiogenic factors, and its actions are primarily mediated through its two membrane receptors, VEGFR‐1 and VEGFR‐2. A soluble form of… Expand
Clinical correlation of brachial artery flow-mediated dilation in patients with systemic sclerosis
ObjectiveTo investigate the clinical significance of flow-mediated dilation (FMD) in systemic sclerosis (SSc).MethodsThirty-three SSc patients and 12 healthy controls were studied. Ultrasound… Expand
Inspiratory muscle training for advanced heart failure with lamin-related muscular dystrophy.
Respiratory muscle weakness is often complicated in patients with heart failure. Its presence further worsens the clinical course of heart failure. However, the effect and appropriate method of… Expand
Melatonin ameliorates Angiotensin II‐induced vascular endothelial damage via its antioxidative properties
Melatonin is well known to have a beneficial effect on the cardiovascular system, but it remains to be elucidated whether melatonin has a therapeutic effect on the vascular damage induced by the… Expand
High-Dose Versus Low-Dose Pitavastatin in Japanese Patients With Stable Coronary Artery Disease (REAL-CAD)
Background: Current guidelines call for high-intensity statin therapy in patients with cardiovascular disease on the basis of several previous “more versus less statins” trials. However, no clear… Expand
Prolonged QRS duration and severity of mitral regurgitation are unfavorable prognostic markers of heart failure in patients with nonischemic dilated cardiomyopathy.
- E. Amiya, K. Tanabe, Y. Ikari, Y. Nakajima, K. Hara
- Circulation journal : official journal of the…
BACKGROUND The goal of the present study was to identify predictors of event-free survival in nonischemic dilated cardiomyopathy (NIDCM) patients after administration of angiotensin-converting enzyme… Expand