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Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.
TLDR
Functional evaluation of selected adenine derivatives in adenylate cyclase assays at 1321N1 astrocytoma cells stably expressing the rAde1R showed that all compounds investigated were agonists or partial agonists.
Adenine and Uracil Derivatives with Antitubercular Activity
TLDR
It was found that a comparatively large, lipophilic fragment is needed in the active molecule to inhibit the tuberculosis pathogen.
Synthesis and N-Alkylation of 6-Benzyloxypurine Under Phase-Transfer Conditions
Abstract Synthesis of 6-benzyloxypurine and its N-alkylation under phase-transfer conditions represents a high-yield and simple procedure for the preparation of 9- and 7-substituted
Effect of immunization with small doses of antigen on the development of experimental atherosclerosis
TLDR
Immunization of rabbits suffering from experimentalhyperlipemia with human gamma-globulin or with disintegrated yeast Candida albicans inhibited the development of hyperlipemia and atherosclerosis.
[HDL2b lipoproteins as an acceptor of cholesterol from erythrocyte membrane and the role of lecithin-cholesterol-acyltransferase during this process].
TLDR
The role of lecithin-cholesterol-acyltransferase (LCAT) in net cholesterol transport from erythrocyte membranes to one of high density lipoprotein subclasses--HDL2b--was studied in vitro and the significance of cholesterol ecceptor properties of HDL2b in vivo is discussed.
Biological clock and the origin of life
A hypothesis about two physical fields that created organic life in Earth's ancient ocean 3–4 billion years ago, and still determine the biological clock phenomenon via changes in the structure of
[Age and dynamics of the chief blood lipid indices among the adult population of Leningrad].
TLDR
Higher levels of HDLPC and lower concentrations of LDLPC in women under 50 as compared with age-matched men account for a later development and milder course of coronary heart disease in premenopausal women.
[Cholesterol content of erythrocytes in humans with different levels of plasma cholesterol].
The mean cholesterol content in erythrocytes of patients, which are not impaired by hepatic diseases is 1.26 +/- 0.02 X 10-13 g/cell and it is not depended on the plasma cholesterol level.
Dark Matter? no Descartes and Kozyrev’s Universe!
Galactic rotation curves explained here as a result of interaction between fast rotating central black hole and stars, which are non-keplerian characters. Black holes are „black” not due to trapping
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