E. A. Eady

Publications103
h-index37
Citations5,135
Highly Influential Citations138
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Inducible erythromycin resistance in staphlyococci is encoded by a member of the ATP‐binding transport super‐gene family
A Staphylococcus epidermidis plasmid conferring inducible resistance to 14‐membered ring macrolides and type B streptogramins has been analysed and the DNA sequence of the gene responsible for… Expand
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Antibiotic‐resistant acne: lessons from Europe
Summary Background Propionibacterium acnes and P. granulosum are widely regarded as the aetiological agents of inflammatory acne. Their proliferation and metabolism are controlled using lengthy… Expand
  • 318
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Distribution of genes encoding erythromycin ribosomal methylases and an erythromycin efflux pump in epidemiologically distinct groups of staphylococci.
Erythromycin-resistant staphylococci can be divided into two phenotypic classes based on their pattern of cross-resistance to other macrolides, lincosamides and type B streptogramins. Strains… Expand
  • 168
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16S rRNA Mutation Associated with Tetracycline Resistance in a Gram-Positive Bacterium
ABSTRACT A genetic basis for tetracycline resistance in cutaneous propionibacteria was suggested by comparing the nucleotide sequences of the 16S rRNA genes from 16 susceptible and 21 resistant… Expand
  • 174
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Staphylococcal resistance revisited: community-acquired methicillin resistant Staphylococcus aureus--an emerging problem for the management of skin and soft tissue infections.
Purpose of reviewIn the community non-localized or deep staphylococcal skin and soft tissue infections are typically managed with β-lactamase stable penicillins. The aims of this review are (1) to… Expand
  • 240
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Detection of transposon Tn5432-mediated macrolide-lincosamide-streptogramin B (MLSB) resistance in cutaneous propionibacteria from six European cities.
Forty-five cutaneous propionibacterial isolates from six European cities were found to be highly resistant to all macrolide-lincosamide-streptogramin B antibiotics, including the ketolide… Expand
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Clinical resistance to erythromycin and clindamycin in cutaneous propionibacteria isolated from acne patients is associated with mutations in 23S rRNA.
The genetic basis of erythromycin resistance in cutaneous propionibacteria was determined by comparing the nucleotide sequences of the peptidyl transferase region in the 23S rRNAs from 9 susceptible… Expand
  • 103
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A variety of gram-positive bacteria carry mobile mef genes.
The mefE gene codes for a membrane bound efflux protein, which confers resistance to macrolides, and has been identified in Streptococcus pneumoniae. A variety of gram-positive organisms were… Expand
  • 162
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Comparison of five antimicrobial regimens for treatment of mild to moderate inflammatory facial acne vulgaris in the community: randomised controlled trial
BACKGROUND We investigated the efficacy and cost-effectiveness of five antimicrobial regimens for mild to moderate facial acne and whether propionibacterial antibiotic resistance affects treatment… Expand
  • 148
  • 5
Staphylococcal resistance revisited: community-acquired methicillin resistant Staphylococcus aureus - an emerging problem for the management of skin and soft tissue infections
Purpose of review In the community non-localized or deep staphylococcal skin and soft tissue infections are typically managed with β-lactamase stable penicillins. The aims of this review are (1) to… Expand
  • 108
  • 5