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  • Influence
Chronic administration of cannabidiol to healthy volunteers and epileptic patients.
In phase 1 of the study, 3 mg/kg daily of cannabidiol (CBD) was given for 30 days to 8 health human volunteers. Another 8 volunteers received the same number of identical capsules containing glucoseExpand
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Cannabidiol interferes with the effects of delta 9 - tetrahydrocannabinol in man.
Abstract Based on previous observations that cannabidiol (CBD) blocks some effects of Δ9-tetrahydrocannabinol (Δ9-THC) in laboratory animals, the present work was carried out to study possibleExpand
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Plants and the central nervous system
  • E. A. Carlini
  • Biology, Medicine
  • Pharmacology Biochemistry and Behavior
  • 1 June 2003
This review article draws the attention to the many species of plants possessing activity on the central nervous system (CNS). In fact, they cover the whole spectrum of central activity such asExpand
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Guarana (Paullinia cupana): toxic behavioral effects in laboratory animals and antioxidants activity in vitro.
The effects on toxic and behavioral levels of guarana (Paullinia cupana) were assessed in rats and mice subsequent to acute and chronic administrations and were compared to those produced by GinsengExpand
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Effects of acute and chronic administration of cannabis sativa and (−)Δ9-trans-tetrahydrocannabinol on the behavior of rats in an open-field arena
The effects of acute and chronic administration of Δ9-THC, cannabis extract and control solution on the behavior of rats repeatedly exposed to an open-field arena have been studied. After the firstExpand
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Effects of cannabidiol on behavioral seizures caused by convulsant drugs or current in mice.
In mice, running, clonic and tonic convulsions and lethality were assessed following transcorneal (electroshock) current or convulsant drugs, each administered alone and after cannabidiol (CBD)Expand
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Pharmacology of lemongrass (Cymbopogon citratus Stapf). I. Effects of teas prepared from the leaves on laboratory animals.
Cymbopogon citratus is one of the most used plants in Brazilian folk medicine for the treatment of nervous and gastrointestinal disturbances. It is also used in many other places to treat feverishExpand
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Household survey on drug abuse in Brazil: study involving the 107 major cities of the country--2001.
The prevalence of the use in Brazil of illicit drugs, as well as of alcohol and tobacco, was determined. Further, illicit use of psychotropic medicines, and anabolic steroids were also surveyed. ThisExpand
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Pharmacology of lemongrass (Cymbopogon citratus Stapf). III. Assessment of eventual toxic, hypnotic and anxiolytic effects on humans.
A herbal tea (called an abafado in Brazil) prepared from the dried leaves of lemongrass was administered to healthy volunteers. Following a single dose or 2 weeks of daily oral administration, theExpand
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