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Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A(More)
BACKGROUND Essential tremor (ET) is the most prevalent inherited movement disorder. ET has been mapped on chromosomes 2 and 3, but causative genes are not known. METHODS We genotyped 16 microsatellite markers in a case-control cohort consisting of 104 patients and 116 controls. RESULTS No significant difference between allele frequencies was found. The(More)
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