E. Timothy Morgan

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RATIONALE Maternal separation (MS) in neonatal rats affects ethanol self-administration (SA) in adulthood; however, the conditions and mechanisms need to be clarified. OBJECTIVES The goal of this study was to determine the effect of MS on ethanol SA in adulthood in different groups of rats, which control for time of separation, handling, and rearing(More)
Lipopolysaccharide (LPS) treatment of rats suppresses CYP 4F4 and 4F5 expression by 50 and 40%, respectively, in a direct fashion occurring in the liver. This contention is borne out by essentially parallel dose-dependent changes observed upon treatment of rat hepatocyte cultures with LPS. An alternate avenue of triggering the inflammatory cascade is(More)
The introduction of concurrency into programs has added to the complexity of the software design process. This is most evident in the design of communications protocols where concurrency is inherent to the behavior of the system. The complexity exhibited by such software systems makes more evident the need for computer-aided tools for automatically(More)
D URABLE-GOODS manufacturing and retail trade were among the leading contributors to the upturn in U.S. economic growth in 2010, according to preliminary statistics on real gross domestic product (GDP) by industry from the Bureau of Economic Analysis. The economic recovery was widespread: 20 of 22 industry groups contributed to real GDP growth. The advance(More)
Cytochrome P450 (CYP) 4F mediated leukotriene B(4) (LTB(4)) metabolism modulates inflammation during injury and infection. Here we show that in addition to LTB(4), the recombinant rat CYP4Fs catalyze omega-hydroxylations of lipoxin A(4), and hydroxyeicosatetraeonic acids. CYP4F gene regulation studies in primary hepatocytes reveal that pro-inflammatory(More)
  • Dylan G. Rassier, Thomas F. Howells, Edward T. Morgan, Nicholas R. Empey, Conrad E. Roesch, Karen Horowitz +2 others
  • 2007
* We thank Baoline Chen for contributing motivation and knowledge to this project through her study to reconcile and balance the 1997 industry accounts (Chen, 2006). We also thank Karen Horowitz, Douglas Meade, Mark Planting, and George Smith for providing early direction, leadership, and advice to the project.
  • Dylan G. Rassier, Thomas F. Howells, Edward T. Morgan, Nicholas R. Empey, Conrad E. Roesch
  • 2007
I N SEPTEMBER, the Bureau of Economic Analysis (BEA) released the 2002 benchmark input-output (I-O) accounts. 1 Benchmark I-O accounts are released every 5 years and provide a detailed picture of the economy, showing relationships among hundreds of industries and commodities. Estimates in the bench­ mark I-O accounts also serve as the statistical founda­(More)
D URABLE-GOODS manufacturing, finance and insurance, and wholesale trade were the leading contributors to U.S. economic growth in 2012, accord­ ing to advance statistics on the breakout of real gross domestic product (GDP) by industry from the Bureau of Economic Analysis (BEA). Overall, 19 of the 22 ma­ jor industry groups contributed to a 2.2 percent in­(More)
We studied the impact of administering XPro1595, a novel antagonist of soluble tumor necrosis factor-α (TNFα), on the regulation of hepatic cytochrome P450 enzymes in the C. rodentium model of infectious colitis. XPro1595 was administered subcutaneously every three days throughout the infection, or as a single injection near the peak of infection. When(More)