E Skaugen

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A nerve membrane model with a two-state pore system was investigated by computer simulation in the uniform (space-clamped) case. Both sodium and potassium conducting pores were modelled, each pore having four independent gates which switched randomly between the open and the closed position, governed by the assumed rate constants. Each pore conducted only(More)
The firing behaviour of simple nerve cell models with a two-state pore system was investigated by computer simulation. The pores were assumed to open and close randomly, with the probabilities for opening an closing calculated from the equations found by Hodgkin and Huxley for the squid giant axon. The cell models had a cell body and an axon with an initial(More)
A stochastic nerve membrane model with a two-state pore system was investigated by computer simulation in the uniform (space-clamped) case. The model was based upon the Hodgkin-Huxley equations for the giant axon in squid, but where both the maximal membrane conductances and the rate constants were changed systematically. This was done in order to simulate(More)
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