E. Shen

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The potential of emotional interaction between human and computer has recently interested researchers in human–computer interaction. The instructional impact of this interaction in learning environments has not been established, however. This study examined the impact of emotion and gender of a pedagogical agent as a learning companion (PAL) on social(More)
Designer support is critical for facilitating collaboration and knowledge construction in an online learning environment. Designer support in this paper refers to the mechanisms that a designer builds in a technology-mediated environment to facilitate online learning. This paper focuses on two aspects of designer support: 1) creating a shared context, and(More)
Mitigating frustration is important within computer-based learning contexts. In this experimental study where participants were purposefully frustrated, the interface agent message (apologetic, empathetic, or silent) was manipulated to investigate its impact on student attitude toward the task, attitude toward the agent, and attribution toward the cause of(More)
This paper describes a two-part study of animated affective agents that varied by affective state (positive or evasive) and motivational support (present or absent). In the first study, all four conditions significantly improved learning; however, only three conditions significantly improved math self-efficacy, the exception being the animated agent with(More)
Glomerular mesangial cells (MCs) hypertrophy is one of the earliest pathological abnormalities in diabetic nephropathy (DN), which correlates with eventual glomerulosclerosis. This study aimed to investigate the therapeutic role of miRNA in diabetic glomerular MCs hypertrophy and synthesis of extracellular matrix (ECM). Microarray analysis revealed a(More)
Lysine is the most limiting essential amino acid for animal nutrition in maize grains. Expression of naturally lysine-rich protein genes can increase the lysine and protein contents in maize seeds. AtMAP18 from Arabidopsis thaliana encoding a microtubule-associated protein with high-lysine content was introduced into the maize genome with the seed-specific(More)
<<The Atlas of Plague and Its Environment in the People's Republic of China>>is the first atlas with spatial analysis methods to study on plague distributions, epidemics, controls, foci characters and their relationships with environment in China. This paper briefly introduces the idea, principle and methodology of its design and the main research results(More)
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