E. S. Kosacheva

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It was shown that the content of serotonin (5-OT) and 5-oxyindoleacetic acid (5-OIAA) in the temporal cortex, hippocampus and medulla oblongata and the content of dopamine and 3,4-dihydroxyphenilacetic acid in the striatum are increased initially, while the level of norepinephrine in the striatum is reduced in Krushinskiĭ-Molodkina rats genetically(More)
The effect of Lamotrigine and carbamazepine on the development and character of the epileptiform seizures after strong sonic stimulation were studied on Krushinskiĭ-Molodkina line of rats. Both drugs manifested a dose-dependent increase in the latency of motor reaction Lamotrigine administration in the dose range of 5-40 mg/kg, i.p., resulted in a moderate(More)
Lamotrigine and carbamazepine (10−3 M) almost completely inhibit electrical activity of neurons in hippocampal slices. The effect of these drugs on signal transmission in the system of Schaffer collaterals/commissural fibers—CA1 hippocampal area pyramidal neurons shows that both anticonvulsants inhibit the excitability of the presynaptic axons and(More)
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