Learn More
BACKGROUND The atherosclerotic progression-reducing effect of LDL cholesterol (LDL-C) lowering has been established in subjects with severe atherosclerotic disease but not in persons with elevated LDL cholesterols without severe atherosclerosis. KAPS (Kuopio Atherosclerosis Prevention Study) is the first population-based trial in the primary prevention of(More)
OBJECTIVES The purpose of this study was to test the hypothesis that the reduction of body iron stores by venesection (blood letting) would reduce the susceptibility to oxidation of atherogenic serum lipoproteins. DESIGN This is a randomized, controlled cross-over trial in 14 regularly smoking men with elevated serum ferritin concentration. The study(More)
OBJECTIVE To test the effect of supplementation of diet with ascorbic acid, selenium, alpha-tocopherol and beta-carotene on the oxidation resistance of very low (VLDL) + low density lipoprotein (LDL). DESIGN A randomized placebo-controlled double-masked clinical trial. SETTING In healthy men aged 30-58 years smoking regularly 15-40 cigarettes/day. (More)
  • 1