E. Penelope Wright

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A survey of two acute district general hospitals (A and B) was undertaken to investigate the extent of methicillin-resistant Staphylococcus aureus (MRSA) contamination of ward-based computer terminals. Of 25 terminals examined, MRSA was identified in six (24%). Environmental contamination was of a low level. Five of the MRSA positive terminals were from(More)
There have been considerable improvements in the collection of health-related quality of life (HRQOL) data in oncology over the past 20 years. The facility with which HRQOL information can now be collected from patients has also been associated with an improved understanding of the meaning of HRQOL and the association between HRQOL and patients' treatment(More)
A steady rise in the number of isolations of Mycobacterium xenopi from patients in a general hospital led to an examination of water taps. Most patients had been accommodated in a group of wards which had a common water supply. This organism was recovered from 35 of 69 outlets, mostly from hot and mixer taps in those wards. Mycobacterium kansasii was also(More)
Two established immunodiagnostic techniques, immunofluorescence and indirect haemagglutination, were compared with ELISA (enzyme-linked immunosorbent assay) using intact promastigotes as antigen for the detection of specific antibodies against Leishmania in the serum of patients with visceral or mucosal leishmaniasis from the Sudan. The ELISA was found to(More)
The commonly used diagnostic methods for visceral leishmaniasis (kala-azar) have many disadvantages. ELISA appears to be a more easily applied test for diagnosis, follow-up of treatment and epidemiology. The preparation of the ELISA antigen has given rise to difficulties in standardization since these are usually soluble. Intact cultured promastigotes have(More)
L. donovani antigens were analyzed by a direct agglutination test (DAT), by ELISA using intact promastigotes and by the SDS-PAGE immunoperoxidase technique (SGIP). Sera of Chagas' disease patients cross-reacted in the ELISA and SGIP but not in the DAT. Trypsin treatment of the parasites removed concanavalin A-binding sites but not epitopes for antibodies(More)
During November and December 1981 more than 50 residents in a village in Derbyshire had an acute gastrointestinal illness. One month later a second outbreak occurred affecting another 22 people. Campylobacter jejuni was isolated from 12 patients; no other gastrointestinal pathogens were identified. A case-control study showed an association with the(More)
A skin test survey was conducted among 1035 children aged 7-19 years living in three cities in Vietnam. Fifteen new tuberculins, including leprosin-A, were applied; an induration of 2 mm diameter or more was considered positive. Compared to some other tropical countries, low levels of sensitisation were recorded and remarkable regional differences were(More)