Learn More
For the diagnosis of somatization disorder, DSM-III requires the assessment of 37 specific symptoms, a time-consuming and cumbersome task. The authors describe a procedure by which the clinician can assess the presence of somatization disorder by screening for only seven symptoms, three of which must be present for a preliminary diagnosis of somatization(More)
After one adaptation night, intramuscular doses of methadone (7.5, 15, 30 mg/70 kg), morphine (10 or 20 mg/70 kg), or placebo were given to seven male nondependent opiate addicts at weekly intervals in a randomized cross-over design. After three adaptation nights, heroin (3, 6, 12 mg/70 kg) was compared with morphine and placebo by means of a similar design(More)
Sixteen analogue scales were designed to measure drug- and illness-related changes in three dimensions of sexual function: interest, arousal, and performance. An orthogonal principal component factor analysis confirmed the three clinical factors. Retest reliability ranged between .80 and .94. Normals (N = 30) reported significantly better functioning than(More)
OBJECTIVE To examine whether minor depression differs from major depression in clinically relevant ways. METHOD Structured interviews, Symptom Checklist-90-Revised (SCL-90-R) scores, and physicians' treatment recommendations were obtained systematically from 1,458 admissions to an outpatient teaching clinic during a 5-year period from 1981 to 1986. Of(More)
Methysergide, a clinically-used blocker of serotonin receptors, was administered to 10 normal young men at a dose of 2 mg every 6 h for 48 h. After drug treatment, serum levels of growth hormone during sleep were 41.9% higher than placebo values (less than 0.001). In contrast, drug treatment was associated with a 36.4% decrease in stimulated growth hormone(More)
The prevalence of psychiatric syndromes among 565 male alcoholic VA inpatients was examined using the structured Psychiatric Diagnostic Interview (PDI). Almost two-thirds fulfilled criteria for one or more additional psychiatric syndromes. Subjects positive only for alcoholism reported a significantly later onset of problem drinking and fewer first-degree(More)
Methysergide a clinically used blocker of serotonin receptors, was given for 48 hr to 11 normal adults, at a dose of 8 mg per 24 hr. Total REM sleep time was decreased, although total sleep time was unchanged. Stage 4 decreased and stage 3 increased, while total slow wave sleep remained constant. There was a tendency toward a decrease in the number of(More)
To examine the relationship between sleep loss and confusion after open-heart surgery, 27 consecutive patients were monitored 1 day preoperatively and 5 days postoperatively with the Folstein Mini-Mental State examination, a modified sleep latency test, and a sleep log. Confusion (low Mini-Mental State scores) peaked on postoperative Days 1 and 2 and(More)