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Advances in imaging technology allow unprecedented access to the anatomy and physiology of the living, growing human brain. Anatomical imaging studies of individuals with attention deficit/hyperactivity disorder (ADHD) consistently point to involvement of the frontal lobes, basal ganglia, corpus callosum, and cerebellum. Imaging studies of brain physiology(More)
mamillo-thalamic tract, anterior thalamic nuclei, cingulate cortex and hippo/parahippocampus), implicated in reward-motivated learning and memory processing, appeared to be involved in these processes. Activation in the septal region in placebo nonresponders recalling was also observed. If confirmed, this effect would be consistent with the memory(More)
Little is known about the process of referral to Irish hospital outpatient medical clinics. We analysed pre-referral management, information quality and communication to a general medical outpatient clinic. 100 consecutive attendee referral letters were prospectively assessed for information, appropriateness, legibility and pre-referral management. Patients(More)
Acute kidney injury (AKI) is a common complication of neonatal encephalopathy (NE). The accurate diagnosis of neonatal AKI, irrespective of the cause, relies on suboptimal methods such as identification of rising serum creatinine, decreased urinary output and glomerular filtration rate. Studies of AKI biomarkers in adults and children have shown that(More)
We report a case of simultaneous presentation of cerebral venous sinus thrombosis and thyrotoxicosis in a 28 year-old female subsequently found to have the Factor V Leiden mutation. She made an excellent neurological recovery with anticoagulation. The mode of presentation of the case was surprising, as she had no thrombotic episodes in two previous(More)
Nationally representative in-hospital mortality rates among preterm infants are essentially unknown in Ireland. We examined preterm infants born in hospital and admitted to intensive care unit (ICU) between 2005 and 2008. Unadjusted incidence rates and risk ratios were derived. Overall, 6,599 preterm infants were admitted to ICU of whom 256 (3.9%) died(More)
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