E. Mamontov

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Many features of living systems prevent the application of fundamental statistical mechanics (FSM) to study such systems. The present work focuses on some of these features. After discussing all the basic approaches of FSM, the work formulates an extension of the kinetic theory paradigm (based on the reduced one-particle distribution function) that exhibits(More)
—The work deals with nonstationary invariant probability distributions of diffusion stochastic processes (DSPs). Few results on this topic are available, such as theoretical works of Il'in and Has'minskiı ˘ and a recent more practical contribution of Mamontov and Willander. This is in a disproportion to an importance of nonstationary invariant DSPs which(More)
We studied the dynamics of hydrated tRNA using neutron and dielectric spectroscopy techniques. A comparison of our results with earlier data reveals that the dynamics of hydrated tRNA is slower and varies more strongly with temperature than the dynamics of hydrated proteins. At the same time, tRNA appears to have faster dynamics than DNA. We demonstrate(More)
A few previous works of the authors derived and discussed the space-time mathematical description, the PhasTraM model, for oncogenic hyperplasia regarded as a genotoxically activated homeorhetic dysfunction. The model is based on the fluid-to-solid-and-back transitions and nonlinear reaction-diffusion equation relevant to a series of the key biomedical(More)
Using quasielastic neutron scattering, we have investigated diffusion dynamics of protons in the protic ionic liquid, N,N,N',N'-tetramethylguanidinium bis(perfluoroethylsulfonyl)imide, a promising new compound for application as an electrolyte in proton-conducting fuel cells. A temperature range of 30-360 K has been studied. The melting temperature of(More)
We study the dynamic susceptibility chi_{T}(Q,t) of deeply supercooled water by means of quasielastic neutron scattering and molecular dynamics simulations. Both techniques show an increase in the peak height of chi_{T}(Q,t) as the temperature is lowered toward the dynamic crossover temperature T_{L} . Below T_{L} , the peak height decreases steadily. We(More)
We use elastic neutron scattering to demonstrate that a sharp increase in the mean-squared atomic displacements, commonly observed in hydrated proteins above 200 K and often referred to as the dynamical transition, is present in the hydrated state of both native and denatured lysozyme. A direct comparison of the native and denatured protein thus confirms(More)
Light activation of the visual G-protein-coupled receptor (GPCR) rhodopsin leads to significant structural fluctuations of the protein embedded within the membrane yielding the activation of cognate G-protein (transducin), which initiates biological signaling. Here, we report a quasi-elastic neutron scattering study of the activation of rhodopsin as a GPCR(More)