E. M. Zubin

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1,2-Diol-oligoribonucleotides were prepared using fully protected 2′-O-[2-(2,3-dihydroxypropyl)amino-2-oxoethyl]uridine 3′-phosphoramidite. Incorporation of the modified uridine residue into oligonucleotide chains was not shown to significantly affect the thermal stability of RNA-RNA and RNA-DNA duplexes. Periodate oxidation of the 1,2-diol group resulted(More)
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