E Lenarcic Liu

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Halopemide, which was identified by HTS to inhibit phospholipase D2 (PLD2), provided the basis for an exploratory effort to identify potent inhibitors of PLD2 for use as inflammatory mediators. Parallel synthesis and purification were utilized to rapidly identify orally available amide analogs derived from indole 2-carboxylic acids with superior potency(More)
INTRODUCTION This study retrospectively evaluated CT-guided thoracic biopsies for diagnostic yield, accuracy and complications. MATERIALS AND METHODS A retrospective analysis of 384 patients (mean age 62.7 years; male/female = 251/133) who underwent 399 CT-guided thoracic biopsies were performed for evaluating diagnostic yield, accuracy and complications.(More)
PURPOSE To assess the feasibility of sleeveless bimanual phacoemulsification using the Millennium Microsurgical System (Bausch and Lomb Surgical) by measuring wound temperature during phacoemulsification. SETTING In vitro laboratory. METHODS The Millennium system was used in 6 eye-bank eyes using pulse mode and 80-milllisecond and 160-millisecond phaco(More)
Undecaprenyl pyrophosphate synthase (UPPS) catalyzes the consecutive condensation of eight molecules of isopentenyl pyrophosphate (IPP) with farnesyl pyrophosphate (FPP) to generate the C(55) undecaprenyl pyrophosphate (UPP). It has been demonstrated that tetramic acids (TAs) are selective and potent inhibitors of UPPS, but the mode of inhibition was(More)
Date The final copy of this thesis has been examined by the signatories, and we find that both the content and the form meet acceptable presentation standards of scholarly work in the above mentioned discipline. Performance of current mesh networks suffer due to the lack of an intelligent physical layer. Research and development in higher layer protocols(More)
We have previously reported that reading-frame usage and functional diversification is developmentally regulated, with virtually all TCRB DJ mRNA transcripts using a single reading frame at 8 weeks of gestational age, tapering to 50% by adult life. We used the polymerase chain reaction to create genomic libraries of DJ rearrangements in the TCRB locus from(More)
Over the past several decades, the frequency of antibacterial resistance in hospitals, including multidrug resistance (MDR) and its association with serious infectious diseases, has increased at alarming rates. Pseudomonas aeruginosa is a leading cause of nosocomial infections, and resistance to virtually all approved antibacterial agents is emerging in(More)
Date The final copy of this thesis has been examined by the signatories, and we find that both the content and the form meet acceptable presentation standards of scholarly work in the above mentioned discipline. Interference Time Analysis for a Cognitive Radio on an Unmanned Aircraft Thesis directed by Prof. Timothy X. Brown This thesis considers a model(More)
A 67-year-old male presented with fatigue, abdominal pain , and 30-pound weight loss over 3 months. Computerized tomography (CT) abdomen displayed ascites with thickening and enhancement of the peritoneum and mottled nodular appearing as soft tissue consistent with omental caking worrisome for peritoneal carcinomatosis. A paracentesis revealed white blood(More)
I would like to cordially invite you to Międzyzdroje, Poland for the 11th IEEE International Conference on Methods and Models in Automation and Robotics. Over 270 draft papers have been submitted, from which the International Program Committee has selected 202 papers for presentation. As before also this year’s Conference is organized under the auspices of(More)
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