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L-DOPA effects on the activities of enzymes controlling the neurotransmitters utilization: monoamine oxidases (MAO) A and B and acetylcholinesterase (AChE) were demonstrated in synaptosomes and mitochondria of the cells in sensorimotor cortex and caudate nucleus. Sixty minutes after a single dose of L-DOPA the MAO and AChE activities were virtually… (More)
The effect of taftsine (T) tetrapeptide was studied on the systemic and subcellular levels. T was found to exert a specific effect on the activities of acetylcholinesterase and MAO molecular forms. The use of T altered the evoked potentials to a signal light stimulus in the cortical and subcortical brain structures. Rearrangements of the membranous proteins… (More)