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Participation of different 5-HT receptors in the memory process in rats and its modulation by the serotonin depletor p-chlorophenylalanine.
The memory effects of agonists and antagonists of some serotonin (5-HT) receptor subtypes were examined in experiments on rats using an active avoidance method (shuttle-box). The 5-HT receptorExpand
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Learning and memory in rats exposed pre- and postnatally to alcohol. An attempt at pharmacological control.
Using conditioned-reflex methods for active and passive avoidance with punishment reinforcement, we found pronounced memory deficits in 12-week old rats exposed perinatally to alcohol (FAS rats).Expand
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Changes in brain opiate receptors in rats with isolation syndrome.
Prolonged social isolation of Wistar rats produces various neurochemical, neuroendocrine and behavioral changes. Some of isolated rats exhibit interspecies aggressive behavior (mouse-killing). It isExpand
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Changes in the brain biogenic monoamines of rats, induced by piracetam and aniracetam.
Single oral dose of 600 mg/kg weight piracetam, respectively 50 mg/kg aniracetam, causes essential changes in the level and turnover of dopamine (DA) and serotonin (5-HT) in some rat cerebralExpand
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Memory effects of standardized extracts of Panax ginseng (G115), Ginkgo biloba (GK 501) and their combination Gincosan (PHL-00701).
In experiments on young (aged 3 months) and old (aged 26 months) rats, using some conditioned-reflex methods with punishment or positive reinforcement for active and passive avoidance (shuttle-box,Expand
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Age-related changes in rat brain dopaminergic receptors.
The number (Bmax) and affinity (Kd) of [3H] spiroperidol binding sites in the cerebral cortex, striatum and hypothalamus of 2-, 10- and 22-month old male Wistar rats (20 rats per group) injected i.Expand
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Enkephalin receptor changes in rat brain during aging.
In experiments on 2-, 10- and 22-month-old rats, it was found that the number (Bmax) of brain enkephalin (Enk) receptors decreased with aging. The Bmax values in the cortex of 22-month-old ratsExpand
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Effects of meclofenoxate on the level and turnover of biogenic monoamines in the rat brain.
The level and turnover of biogenic monoamines in some rat brain structures were determined after treatment with meclofenoxate at a dose of 50 mg/kg administered i.p. two times a day (9 a.m. and 5Expand
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Effect of CDP-choline on learning and memory processes in rodents.
The effects of cytidine (5') diphosphocholine (CDP-choline) on learning and memory were studied using conditioned reflex methods for passive avoidance and active avoidance with punishmentExpand
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Memory effects of the Ca2+ and 5-HT antagonists dotarizine and flunarizine.
In experiments on Wistar and Long Evans rats, using behavioral methods for passive (step-down and step-through) and active (shuttle-box two-way avoidance with punishment reinforcement) the newlyExpand
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