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Pregnancy-induced expansion of regulatory T-lymphocytes may mediate protection to multiple sclerosis activity.
Pregnancy represents a physiological transitory state of immune tolerance to avoid the rejection of the foetus, and concomitantly of stabilisation of many autoimmune diseases, such as multipleExpand
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Multicenter study for the evaluation of the antibody response against salmonella typhi Vi vaccination (EMPATHY) for the diagnosis of Anti-polysaccharide antibody production deficiency in patients
Abstract Evaluation of specific antibody (Ab) response to polysaccharide antigens is essential for diagnosis of primary immunodeficiencies. We assessed the specific Ab responses to theExpand
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Sequential combined therapy with omalizumab and rituximab: a new approach to severe atopic dermatitis.
BACKGROUND Atopic dermatitis (AD) is a common chronic skin disease, and a significant percentage of AD patients have severe forms. Inflammation based on type 2 helper T cells (T(H)2), autoantibodies,Expand
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Experience in IVIg Therapy for Selected Women with Recurrent Reproductive Failure and NK Cell Expansion
Recurrent reproductive failure (RRF) has been associated with expansion of circulating NK cells, key cells for maternal tolerance, decidual vasculogenesis and embryo growth. This study reports ourExpand
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Intravenous Immunoglobulin Treatment Increased Live Birth Rate in a Spanish Cohort of Women with Recurrent Reproductive Failure and Expanded CD56+ Cells
Natural killer (NK, CD3− CD56+/CD16+) and NKT‐like cells (CD3+ CD56+/CD16+) activity is considered among the key factors for reproductive success. In the absence of immunological screening,Expand
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Immunological abnormalities in primary APS evolving into SLE: 6 years follow-up in women with repeated pregnancy loss
We have performed a prospective study to determine the prevalence of immunological abnormalities and the evolution from primary antiphospholipid syndrome (APS) into systemic lupus erythematosus (SLE)Expand
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Partial Response to Anti‐CD20 Monoclonal Antibody Treatment of Severe Immune Thrombocytopenic Purpura in a Patient with Common Variable Immunodeficiency
Abstract: Immune thrombocytopenic purpura (ITP), alone or in combination with autoimmune hemolytic anemia (Evans syndrome) and/or autoimmune neutropenia, is frequent in patients with common variableExpand
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Isolated type 5 antimitochondrial autoantibodies are associated with a history of thrombocytopenia and fetal loss.
OBJECTIVE To report an unusual case of clinical antiphospholipid syndrome seen with recurrent fetal loss, chronic thrombocytopenia, and recurrent idiopathic thrombocytopenic purpura, in which theExpand
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